山东大学学报(医学版) ›› 2014, Vol. 52 ›› Issue (10): 72-76.doi: 10.6040/j.issn.1671-7554.0.2014.222
姜丽丽1, 马喆2, 马楚云3, 何远流1, 陶国伟2, 刘村1, 耿群4, 汤婷婷5, 王音4
JIANG Lili1, MA Zhe2, MA Chuyun3, HE Yuanliu1, TAO Guowei2, LIU Cun1, GENG Qun4, TANG Tingting5, WANG Yin4
摘要: 目的 探讨声脉冲辐射力成像技术(ARFI)中声触诊组织定量技术(VTQ)在甲状腺良、恶性结节鉴别诊断中的应用。方法 选择山东大学齐鲁医院超声科2011年9月至2012年10月期间,经超声VTQ检测并手术或穿刺活检后病理证实的312个甲状腺结节(来自268例患者),据病理结果分为良性结节组(n=196)和恶性结节组(n=116),以相应的结节周围组织为良性结节周围组(n=196)和恶性结节周围组(n=116),对各组的VTQ检测结果进行回顾性分析并做统计学处理。结果 ①恶性结节组的VTQ测值显著高于其他3组(P<0.001);②良性结节组的VTQ测值与良性结节周围组、恶性结节周围组无显著差异(P=0.174、P=0.812、P=0.063)。③据ROC曲线计算约登指数,确定界值3.25 m/s,为ROC曲线上的最佳临界点,对应的敏感度为89%,特异度为70%。结论 超声VTQ技术对甲状腺良、恶性结节具有重要的鉴别诊断作用。
中图分类号:
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