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山东大学学报(医学版) ›› 2010, Vol. 48 ›› Issue (8): 113-116.

• 论文 • 上一篇    下一篇

对非酒精性脂肪肝患者生活方式干预的效果评价

章蓉1,2,吴凤芸2,徐贵发1   

  1. 1.山东大学公共卫生学院, 济南 250012;  2.青岛市市立医院超声科, 山东 青岛 266071
  • 收稿日期:2010-06-25 出版日期:2010-08-16 发布日期:2010-08-16
  • 通讯作者: 徐贵发,男,教授,主要从事营养与食品卫生学的研究。E-mail:yyxu@sdu.edu.cn
  • 作者简介:章蓉(1963- ),女,副主任医师,硕士研究生,主要从事营养与食品卫生学的研究。

Effectiveness of   lifestyle intervention in nonalcoholic fatty liver disease

ZHANG Rong1,2, WU  Feng-yun2, XU  Gui-fa1   

  1. 1. School of Public Health, Shandong University, Jinan 250012, Chiha;
    2. Departmenrt of Ultrasound, Qingdao Municipal  Hosipital,  Qingdao 266071,  Shandong,  China
  • Received:2010-06-25 Online:2010-08-16 Published:2010-08-16

摘要:

目的    评估生活方式干预对非酒精性脂肪肝患者的治疗效果。方法    对105名非酒精性脂肪肝患者实施生活方式干预,包括健康教育、饮食干预与运动干预。根据超声诊断标准,将脂肪肝分为轻、中、重度3组,其中轻度组64人,中度组35人,重度组6人,并采用氯化酶法检测患者的血脂指标包括甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白(LDL)、高密度脂蛋白(HDL),12个月后复查超声及血脂指标,对其效果进行分析评估。结果    干预后,轻度组中有40人消除脂肪肝(P<0.01);中度组中有28人转变成轻度脂肪肝,有3人消除脂肪肝(P<0.01);重度脂肪肝中有3人转变成中度脂肪肝(P<0.05);干预后TG 、TC、 LDL较干预前降低(P<0.05)。结论    对非酒精性脂肪肝患者进行生活方式干预,可降低脂肪肝的发病率,提高脂肪肝的逆转率。

关键词: 非酒精性脂肪肝;生活方式;饮食干预;运动干预

Abstract:

Objective    To evaluate therapeutic effectiveness of lifestyle intervention in non-alcoholic fatty liver disease. Methods    105 cases of  non-alcoholic fatty liver patients were enrolled.  Lifestyle interventions was applied to all of them, including learning knowledge of health, dietary control and exercises .There were 64 mild ,35 moderate  and 6 severe cases  diagnosed by ultrasonic tomography. Triglyceride (TG), total cholesterol(TC), HDL-cholesterol (HDL) and LDL-cholesterol(LDL) were also measured. After 12 months of therapy, the effectiveness was finally evaluated. Results    After 12-month lifestyle intervention, 40 mild fatty liver recovered to normal(P<0.01) while among moderate cases, 28 turned into mild and 3 recovered to normal(P<0.01). 3 severe cases became moderate(P<0.05). And TG、TC、LDL decreased significantly. Conclusion    Lifestyle intervention can effectively reduce the morbidity rate and increase the recovery rate in non-alcoholic fatty liver patients.

Key words: Non-alcoholic fatty liver; Lifestyle; Dietary intervention; Exercise intervention

中图分类号: 

  • R575.5
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