不同平台对大鼠Morris水迷宫学习记忆能力的影响

doi:10.6040/j.issn.1671-7554.1.2014.004

山东大学学报（医学版） ›› 2014, Vol. 52 ›› Issue (7): 7-10.doi: 10.6040/j.issn.1671-7554.1.2014.004

不同平台对大鼠Morris水迷宫学习记忆能力的影响

张玉霞, 李玥, 宋涛

中国科学院电工研究所生物电磁技术研究部, 北京 100190

收稿日期:2014-03-17 修回日期:2014-06-26 出版日期:2014-07-10 发布日期:2014-07-10
通讯作者: 宋涛。E-mail：songtao@mail.iee.ac.cn E-mail:songtao@mail.iee.ac.cn
基金资助:
国家自然科学基金（81200996）

Effects of different platforms on the learning and memory capability of rats in the Morris water maze

ZHANG Yuxia, LI Yue, SONG Tao

Research Department of Biological Electromagnetic Technology, Institute of Electrical Engineering, Chinese Academy of Sciences, Beijing 100190, China

Received:2014-03-17 Revised:2014-06-26 Online:2014-07-10 Published:2014-07-10

摘要/Abstract

摘要： 目的探讨水迷宫不同形状逃避平台对大鼠学习记忆能力的影响。方法选用44只健康雄性SD大鼠，利用Morris水迷宫装置检测学习记忆能力，并观察两种不同形状（圆柱形和杆状）逃避平台对大鼠学习记忆的影响。结果逃避潜伏期结果显示，两种平台潜伏期无统计学差异（P>0.05）；空间探索实验结果也无统计学差异（P>0.05）。结论两种形状逃避平台对大鼠学习记忆能力无明显影响。

关键词: 形状, 平台, 学习记忆, Morris水迷宫

Abstract: Objective To study the effects of platforms with different shapes on learning and memory capability using the Morris water maze. Methods Morris water maze was used to detect learning and memory capability of 44 healthy male SD rats. Two escape platforms with different shapes(cylinder or rod) were used to investigate the effects of different platforms on learning and memory capability. Results The data of escape latency showed no significant difference(P>0.05). There was no significant difference in probe trial(P>0.05). Conclusion Platforms with different shapes do not affect the learning and memory capability in Morris water maze.

Key words: Shape, Platform, Morris water maze, Learning and memory

中图分类号:

R338.64

张玉霞, 李玥, 宋涛. 不同平台对大鼠Morris水迷宫学习记忆能力的影响[J]. 山东大学学报（医学版）, 2014, 52(7): 7-10.

ZHANG Yuxia, LI Yue, SONG Tao. Effects of different platforms on the learning and memory capability of rats in the Morris water maze[J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2014, 52(7): 7-10.

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不同平台对大鼠Morris水迷宫学习记忆能力的影响

Effects of different platforms on the learning and memory capability of rats in the Morris water maze

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