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山东大学学报 (医学版) ›› 2020, Vol. 1 ›› Issue (7): 115-121.doi: 10.6040/j.issn.1671-7554.0.2020.0080

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心血管疾病患者健康相关生命质量及其影响因素的多水平模型分析

邓清文,刘文彬   

  1. 福建医科大学公共卫生学院卫生管理学系, 福建 福州 350122
  • 出版日期:2020-07-20 发布日期:2020-07-10
  • 通讯作者: 刘文彬. E-mail:wenbinliu126@126.com
  • 基金资助:
    福建省高校杰出青年科研人才培育计划(2018B030)

Multilevel analysis of health related quality of life of patients with cardiovascular disease and its determinants

DENG Qingwen, LIU Wenbin   

  1. Department of Health Management, School of Public Health, Fujian Medical University, Fuzhou 350122, Fujian, China
  • Online:2020-07-20 Published:2020-07-10

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摘要： 目的 探讨心血管疾病患者的健康相关生命质量及其影响因素,为改善患者生命质量提供参考。 方法 选取2015年中国健康与养老追踪调查(CHARLS)中符合要求的心血管疾病患者1 201例,收集患者及地区信息,基于欧洲五维健康量表(EQ-5D-3L)测量健康效用值反映其健康相关生命质量。采用K-W检验对患者和地区因素进行单因素分析。以患者水平为水平1,地区水平为水平2,建立两水平回归模型,分析患者和地区因素对心血管疾病患者健康相关生命质量的影响。 结果 健康效用值平均值为0.749±0.166。单因素分析结果显示,心血管疾病患者健康相关生命质量的影响因素包括性别、受教育水平、婚姻状况、是否患有高血压、是否患有心脏病、是否患有中风、睡眠时长、吸烟状况、饮酒状况、每周中等强度体力活动时间、社交活动频率、体质量指数(BMI)、所在地区(P<0.05)。多水平模型结果显示,对心血管疾病患者健康相关生命质量有显著影响的因素有性别、受教育水平、婚姻状况、是否患有高血压病、是否患有血脂异常、是否患有心脏病、是否患有中风、吸烟状况、每周中等强度体力活动时间、社交活动频率、BMI以及地区水平的地区因素(P<0.05)。 结论 提高心血管疾病患者的健康相关生命质量既要考虑受教育水平、吸烟状况、BMI等个体因素,还应考虑不同地区患者的异质性,从而制定不同地区的针对性策略。

关键词: 心血管疾病, 健康相关生命质量, 健康效用值, 多水平回归模型, 欧洲五维健康量表

Abstract: Objective To explore health related quality of life(HRQoL)of patients with cardiovascular disease(CVD)and identify the influencing factors. Methods A total of 1 201 CVD patients eligible for the research requirements were selected from CHARLS investigation. Patients information and regions were collected. HRQoL was measured using EQ-5D-3L scale. Patients information and regions were analyzed with K-W test. With patient as level 1 and region as level 2, a two-level regression model was set up to identify the influencing factors. Results The mean health utility value was 0.749±0.166. Univariate analysis showed that determinants of HRQoL of CVD patients included gender, educational level, marital status, hypertension, heart disease, stroke, sleep duration, smoking status, drinking status, minutes of moderate-intensity physical activity per week, frequency of social activity, body mass index(BMI)and region(P<0.05). Multilevel model results indicated that determinants of HRQoL of CVD patients were gender, education level, marital status, hypertension, dyslipidemia, heart disease, stroke, smoking status, minutes of moderate-intensity physical activity per week, frequency of social activity, BMI and region(P<0.05). Conclusion To improve quality of life of CVD patients, education level, smoking status, BMI and heterogeneity of different regions should be considered so as to develop targeted strategies.

Key words: Cardiovascular disease, Health related quality of life, Health utility value, Multilevel model, EQ-5D-3L scale

中图分类号: 

  • R181.3
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