控制牙菌斑对胃粘膜幽门螺旋杆菌检出率的影响

山东大学学报(医学版)

控制牙菌斑对胃粘膜幽门螺旋杆菌检出率的影响

贾春玲¹，杨学馨¹，王磊¹，李翠荣²

山东大学齐鲁医院 1．口腔科； 2．消化内科，济南 250012

收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2008-08-16 发布日期:2008-08-16
通讯作者: 贾春玲

Control of dental plaque on helicobacter pylori in gastric mucosa

JIA Chun-ling¹, YANG Xue-xin¹， WANG Lei¹, LI Cui-rong²

1. Department of Stomatology; 2. Department of Gastroenterology, Qilu hospital of Shandong University， Jinan 250012， China

Received:1900-01-01 Revised:1900-01-01 Online:2008-08-16 Published:2008-08-16
Contact: JIA Chun-ling

摘要/Abstract

摘要：

目的〓〖HTK〗通过检测胃粘膜幽门螺旋杆菌（HP），观察控制牙菌斑对胃粘膜ＨＰ检出率的影响，探讨口腔和胃内ＨＰ的相关性。〖HTW〗方法〓〖HTK〗将根除胃内ＨＰ的患者108例分为试验组（n=56）和对照组（n=52）。试验组行彻底的牙菌斑控制，对照组未行牙菌斑控制或控制失败。半年后均行胃镜复查，并行病理检查和快速尿素酶试验检测胃内ＨＰ，确定其检出率。〖HTW〗结果〓〖HTK〗试验组56例患者中胃ＨＰ阳性者11例，检出率为19.6%；对照组52例患者中胃ＨＰ阳性者42例，检出率为80.8%，试验组胃粘膜中ＨＰ的检出率明显低于对照组（P＜0.05）。〖HTW〗结论〓〖HTK〗口腔与胃ＨＰ感染之间具有明显相关性。提示治疗ＨＰ相关性胃病时，应注意口腔卫生，控制牙菌斑。

关键词: 幽门螺旋杆菌, 检出率, 胃粘膜, 牙菌斑

Abstract:

Objective〓〖WTBZ〗To explore the relationship between oral and gastric mucosa helicobacter pylori (H. pylori). 〖WTHZ〗Methods〓〖WTBZ〗108 patients without H. pylori in their gastric mucosa were assigned into the experimental group (n=56) and the control group (n=52). Dental plaque was completely controlled in the experimental group and was not controlled or not successfully controlled in the control group. All patients re-underwent endoscopies after half a year. By endoscopies, biopsies were taken from the gastric mucosa. Histological examination and rapid Urease test were used to determine the presence of H. pylori. 〖WTHZ〗Results〓〖WTBZ〗H. pylori was found in 11 cases (19.6%) in the experimental group and 42 cases (80.8%) in the control group. The presence of H. pylori was significantly lower in the experimental group than that in the control group (P＜0.05). 〖WTHZ〗Conclusion〓〖WTBZ〗There are significant relationships between oral and gastric H. pylori infection, indicating dental plaque should be controlled in treatment of H. pylori-related gastric diseases.

Key words: Dental plaque, Gastric mucosa, Helicobacter pylori, Detection rate

中图分类号:

R573.1

贾春玲,杨学馨,王磊,李翠荣 . 控制牙菌斑对胃粘膜幽门螺旋杆菌检出率的影响[J]. 山东大学学报(医学版), 2008, 46(8): 807-808.

JIA Chun-ling,YANG Xue-xin,WANG Lei,LI Cui-rong. Control of dental plaque on helicobacter pylori in gastric mucosa[J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2008, 46(8): 807-808.

参考文献

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