不同年龄房间隔缺损封堵术后心脏电生理及几何形态的变化

山东大学学报(医学版)

不同年龄房间隔缺损封堵术后心脏电生理及几何形态的变化

靳有鹏，王玉林，韩波，刘廷亮，张建军，庄建新，韩秀珍，汪翼，马沛然

山东大学山东省立医院儿科，山东济南 250021

收稿日期:2006-02-09 修回日期:1900-01-01 出版日期:2006-08-24 发布日期:2006-08-24
通讯作者: 靳有鹏

Electrical and geometric changes after percutaneousclosure of atrial septal defect

JIN You-eng,WANG Yu-in,HAN Bo,LIU Ting-iang,ZHANG Jian-un,ZHUANG Jian-in, HAN Xiu-hen,Wang Yi,MA Pei-an

Department of Pediatrics, Shandong Provincial Hospital, Shandong University, Jinan 250021, Shandong, China

Received:2006-02-09 Revised:1900-01-01 Online:2006-08-24 Published:2006-08-24
Contact: JIN You-eng

摘要/Abstract

摘要： 目的：了解不同年龄患者经导管房间隔缺损(ASD)堵闭术后心脏电生理及几何形态的变化。方法：100例ASD患者，按年龄分为儿童组和成人组，对比研究其经导管堵闭术前及术后1?d、1个月、3个月心电图(ECG) 及经胸超声心动图(TTE) 测量指标的变化，ECG指标包括PR间期、QRS时限、 II导联P波振幅(PII)、RV1+SV5等，TTE指标有右心室舒张末期内径(RVDD)、左心室舒张末期内径(LVDD)、右室/左室(RVDD/LVDD)比率、收缩末期左房横径(LALD)、右房横径(RALD)、RALD/LALD及左室射血分数(LVEF)等。结果：儿童组患者术后1?d与术前相比， RALD由(36±7)mm降至(34±8)mm，RVDD由(30±8)mm降至(26±7)mm，LVEF由(64±7)%升至(69±6)%；术后1个月时，LALD由(29±7)mm增至(32±8)mm， LVDD由(36±6)mm升至(39±6)mm；术后3个月时，PR间期由(136±20)ms降至(125±13)ms，以上指标均有统计学意义；成人组与儿童组变化相似；两组的QRS时限、PII和RV1+SV5至术后3个月时仍无显著变化。结论：继发孔型房间隔缺损的介入治疗减轻了右心的容量负荷，使心脏的电生理改变恢复正常，逆转了心脏重构，对不同年龄的患者均有良好效果。

Abstract: To investigate the electrical and geometric changes of heart after percutaneous closure of atrial septal defect (ASD). Methods: A total of 100 patients received percutaneous closure of ASD, and were measured standard 12lead electrocardiography (ECG) and transthoracic echocardiography(TTE) before closure, 24 hours, 1 month and 3months after closure. The items of ECG included PR interval, QRS duration, PII and RV1+SV5, and that of TTE included the diastolic diameter of right ventricle(RVDD) and left ventricle(LVDD), RVDD/LVDD ratio, the lateral diameter of left atrial (LALD) , the lateral diameter of right atrial (RALD), RALD/ LALD ratio and ejection fraction(EF) of LV. Results: In all patients, the PR interval, RVDD, RALD, RVDD/LVDD and RALD/ LALD ratio decreased and LVDD, LALD, EF increased significantly after closure, but QRS duration, PII and

Key words: Atrial septal defect, Percutaneous closure, Electrocardiography, Transthoracic echocardiography

靳有鹏,王玉林,韩波,刘廷亮,张建军,庄建新,韩秀珍,汪翼,马沛然. 不同年龄房间隔缺损封堵术后心脏电生理及几何形态的变化[J]. 山东大学学报(医学版), 2006, 44(8): 806-809.

JIN You-eng,WANG Yu-in,HAN Bo,LIU Ting-iang,ZHANG Jian-un,ZHUANG Jian-in,HAN Xiu-hen,Wang Yi,MA Pei-an. Electrical and geometric changes after percutaneousclosure of atrial septal defect[J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2006, 44(8): 806-809.

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