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年龄和性别对急性心肌梗死住院患者预后的影响

王晓荣,季晓平,蒋世亮,季晓华,宋兆峰,王荣,张蕾   

  1. 1.教育部和卫生部心血管重构与功能研究重点实验室, 山东大学齐鲁医院心内科,山东 济南 250012;2.莱州市人民医院放射科,山东 莱州 261400
  • 收稿日期:2006-05-04 修回日期:1900-01-01 出版日期:2006-06-24 发布日期:2006-06-24
  • 通讯作者: 王晓荣

WANG Xiao-rong   

  1. 1.Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education andPublic Health, Department of Cardiology, Qilu Hospital of Shandong University, Jinan 250012, Shandong, China
  • Received:2006-05-04 Revised:1900-01-01 Online:2006-06-24 Published:2006-06-24
  • Contact: WANG Xiao-rong

摘要: 目的:探讨年龄和性别对急性心肌梗死(AMI)住院患者预后的影响。方法:回顾性研究1994年1月至2004年12月期间在我院住院且未行再灌注治疗的全部AMI病例,对比不同年龄和性别AMI患者住院期间缺血复发(包括心绞痛和再梗死)、心力衰竭和死亡发生率的差异。结果:共有1?315例患者入选,男性897例,女性418例。在≤60岁, 61~80岁和≥81岁三个不同的年龄组,女性患者比例随年龄的增长而增加(分别为18.4%、 37.8%和53.8%,P均<0.05);心力衰竭和死亡的发生率随年龄的增长而增加(分别为16.0%、30.0%、49.2%和4.1%、10.0%、32.3%, P均<0.05);缺血复发率无统计学意义。女性患者住院期间心力衰竭和死亡的发生率高于男性患者(分别为34.4% vs 22.1%, P<0.001;11.7% vs 7.8%, P<0.05),排除年龄因素后,性别对死亡率的影响无统计学意义。结论:AMI患者住院期间心力衰竭和死亡的发生率随年龄增长而增加;女性患者心力衰竭发生率显著高于男性,死亡率也高于男性,但排除年龄因素后,不同性别死亡率的差异未达统计学意义。

Abstract: o evaluate the impact of age and sex on inhospital outcomes of patients with acute myocardial infarction(AMI). Methods: A retrospective study was carried out in patients with AMI who were admitted to Qilu hospital from January 1994 to December 2004 and had never experienced any sorts of reperfusion therapy including thrombolysis, primary percutaneous coronary intervention (PCI) and CABG within the first 24 hours after symptom onset. Results: A total of 1,315 patients including 897 males and 418 females were enrolled in this study. The distribution of ages was: ≤60 years, 462 patients (35.1%), 61 to 80 years, 788(59.9%), and≥81 years

Key words: Acute myocardial infarction, Age factors, Sex factors, Prognosis, Complications

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