Abstract: Objective: Flow cytometry crossmatch (FCXM) has been extensively used in kidney transplantation, but there is no agreement regarding its predictive value for oneyear graft loss following kidney transplantation. The aim of the study was to explore the relationship between FCXM and oneyear graft loss following kidney backward stepwise method. Results: Graft loss occurred in 30 subjects during the followup, and 23 graft losses happened in the first year following kidney transplantation. χ2 test showed that there was no statistical difference regarding oneyear graft loss between FCXM positive and negative groups. Logistic regression showed that the significant predictors for oneyear graft loss were delayed graft function (OR=8.00, P=0.001?4), cadaver donor (OR=9.30, P=0.001?7) and vascular rejection (OR=5.05, P=0.021?9). FCXM was not a significant predictor with an odds ratio of 1.60 (P=0.534?6). Conclusion: FCXM has no predictive value for oneyear graft loss following kidney transplantation.transplantation. Methods: χ2 test was used to compare oneyear graft loss rate between FCXM positive and negative groups. Logistic model was built to measure the association between flow cytometry crossmatch and oneyear graft loss, and model variables included early acute rejection, vascular rejection, delayed graft function, positive FCXM, panel reactive antibody, HLAA, B mismatch number, HLADR mismatch number, donor resource, transplantation history, cold ischemic time, donor and recipient age and immunosuppression medication. The final model was determined by th

Key words: Kidney transplantation, Crossmatch, Regression analysis