JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES)

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Brachytherapy by CTguided percutaneous paracentesis implantation of iodine125 seeds for lung cancer

WANG Jing,LI Zhen-jia,WANG Xian-feng,MING De-guo,CHI Xiang-yu   

  1. 1. Department of Respiratory Diseases， Shandong Provincial Hospital, Shandong, University, Jinan 250021, Shandong, China； 2. Shandong Institute of Medical Imaging， Jinan 250021, Shandong, China
  • Received:2006-03-29 Revised:1900-01-01 Online:2006-10-24 Published:2006-10-24

Abstract: To explore the clinical value of 125Methods: Implantation of iodine125 seeds with implanting needle (18gauge) by optical navigating system was carried out in fiftythree patients with lung cancer. After operation， the size of tumors and the changes of blood were observed. Results： The fiftythree patients, with sixtytwo focuses, were given eightyone punctures and observed for more than six months. Twelve of the patients were implanted again. The response rate of one, two, three and six months after operation was 33.87%(21/62), 51.61%(32/62),91.94%(57/62) and 95.16%(59/62) respectively. There were no significant changes in peripheral blood cells, liver functions, renal functions, T cell subgroups and the activity of natural killer cells after operation. Pneumothorax and hemoptysis were seen in 5(6.17%,5/81) and 9 (11.11%,9/81) patients respectively. Conclusion: Brachytherapy by CTguided percutaneous paracentesis implantation of iodine125 seeds is effective and safe for the treatment of lung cancer. The complication is rare and easy to treat.

Key words: Iodine125, Brachytherapy, Lung neoplasms

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