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山东大学学报 (医学版) ›› 2022, Vol. 60 ›› Issue (7): 43-47.doi: 10.6040/j.issn.1671-7554.0.2022.0166

• 子宫腺肌病研究专题 • 上一篇    下一篇

子宫腺肌病合并不孕的治疗

颜磊,陈子江   

  1. 山东大学附属生殖医院妇科, 山东 济南 250021
  • 发布日期:2022-07-27
  • 通讯作者: 颜磊. E-mail:yanlei@sdu.edu.cn
  • 基金资助:
    国家自然科学基金(82072627)

Treatment of adenomyosis complicated with infertility

YAN Lei, CHEN Zijiang   

  1. Department of Gynecology, Center for Reproductive Medicine, Shandong University, Jinan 250021, Shandong, China
  • Published:2022-07-27

摘要: 子宫腺肌病可导致不孕和流产,可增加体外受精-胚胎移植(IVF-ET)的流产率、降低活产率和临床妊娠率,也增加产科和新生儿相关并发症。经阴道超声已成为子宫腺肌病的一线诊断方法,但需提高诊断率。子宫腺肌病合并不孕症的治疗方法包括药物、手术、介入治疗和辅助生殖助孕治疗等。一般情况下可推荐首选IVF,一般推荐GnRH-a的应用和全胚冷冻策略。针对子宫腺肌病的诊断、非IVF治疗方法的效果、GnRH-a预处理以及鲜胚、冻胚移植比较等问题仍需进行更多研究。

关键词: 子宫腺肌病, 不孕症, 体外受精, 胚胎移植

Abstract: Adenomyosis can cause infertility and miscarriage, increase the miscarriage rate of in vitro fertilization intracytoplasmic sperm injection and embryo transfer(IVF-ET), reduce the live birth rate and clinical pregnancy rate, and increase obstetric and neonatal complications. Transvaginal ultrasound has become the first-line diagnostic method of adenomyosis, but the accuracy needs to be improved. The treatment of adenomyosis complicated with infertility includes drug, surgical, interventional therapy and assisted reproduction therapy, et al. IVF is generally recommended as the first choice, and GnRH-a and freeze-all strategy are also recommended. More research is needed to explore the diagnosis of adenomyosis, efficacy of non-IVF treatment, pretreatment of GnRH-a, and comparison of fresh versus frozen embryo transplantation.

Key words: Adenomyosis, Infertility, In vitro fertilization intracytoplasmic sperm injection, Embryo transfer

中图分类号: 

  • R711.74
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