4例继发性肥大性下橄榄核变性的临床及影像学特点

doi:10.6040/j.issn.1671-7554.0.2021.0969

摘要/Abstract

摘要： 目的探讨继发性肥大性下橄榄核变性(HOD)临床及影像学特点,提高临床识别及诊断率。方法回顾分析2019年4月至2020年1月收治的4例HOD患者临床资料,归纳临床、影像特点,探讨其发生机制。结果 4例患者均为继发性HOD,脑干、小脑不同病变在锥体系症状好转的基础上出现锥体外系症状。磁共振(MRI)T₂成像示下橄榄核局限性高信号伴体积增大。结论脑干、小脑病变可导致继发性肥大性HOD。当锥体系症状平稳时出现锥体外系症状,需考虑HOD,结合影像检查可明确诊断。

关键词: 继发性肥大性下橄榄核变性, 临床特征, 影像学表现

Abstract: Objective To explore the clinical and imaging characteristics of secondary hypertrophic olivary degeneration(HOD)so as to improve the clinical recognition and diagnosis. Methods The clinical and imaging data of 4 patients treated during Apr. 2019 and Jan. 2020 were retrospectively analyzed, and the mechanism was discussed. Results All cases were secondary HOD. Symptoms of extra-vertebral system appeared, while symptoms of pyramidal system in different lesions of the brainstem and cerebellum were stable. Limited high signal was observed in the enlarged inferior olivary nucleus on T₂WI imaging. Conclusion Variant lesions in brain stem or cerebellum may lead to the occurrence of secondary HOD. When extra-vertebral system symptoms appear in addition to stable vertebral system symptoms, HOD should be considered. A clear diagnosis requires appropriate imaging examinations.

Key words: Secondary hypertrophic olivary degeneration, Clinical manifestation, Imaging characteristics

中图分类号:

R742

巩雨,高震,王虎清,杨晶雯,张桂莲,展淑琴,张茹,吴海琴. 4例继发性肥大性下橄榄核变性的临床及影像学特点[J]. 山东大学学报 (医学版), 2022, 60(5): 37-42.

GONG Yu, GAO Zhen, WANG Huqing, YANG Jingwen, ZHANG Guilian, ZHAN Shuqin, ZHANG Ru, WU Haiqin. Clinical and imaging characteristics of 4 cases of secondary hypertrophic olivary degeneration[J]. Journal of Shandong University (Health Sciences), 2022, 60(5): 37-42.

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