中药熏蒸联合体外冲击波对72例髋关节撞击综合征临床疗效、血清炎症因子水平的影响

doi:10.6040/j.issn.1671-7554.0.2022.0030

摘要/Abstract

摘要： 目的观察分析中药熏蒸联合体外冲击波治疗髋关节撞击综合征的临床疗效及对血清炎症因子水平的影响。方法选取2019年12月至2021年9月黑龙江中医药大学附属第一医院门诊及住院部收治的髋关节撞击综合征患者72例,按随机数字表法分为观察组和对照组,每组36例。对照组采用体外冲击波治疗,冲击波采取发散模式,压力设定为2.0~3.0 bar,每次治疗冲击3 000~4 000次,每3 d治疗1次。观察组在对照组的治疗基础上,进行中药熏蒸治疗,30 min/次,1次/d。两组分别治疗30 d。比较治疗前及治疗后4周的视觉模拟(VAS)评分、髋关节功能(HHS)评分、血清基质金属蛋白酶-13(MMP-13)、白细胞介素1β(IL-1β)水平、生活质量以及疗法安全性,所有数据采用SPSS26.0统计学软件进行分析,评价临床疗效。结果治疗后观察组总有效率高于对照组(P<0.05),两组VAS、HHS评分均较治疗前改善,组间对比显示,观察组治疗后VAS、HHS评分改善较对照组明显(P<0.05);两组治疗后炎症因子MMP-13、IL-1β水平均较治疗前降低,组间对比显示,观察组治疗后炎症因子MMP-13、IL-1β水平低于对照组(P<0.05);两组治疗后生活质量评分较治疗前增高,组间对比显示,观察组治疗后生活质量评分高于对照组(P<0.05);两组治疗后安全性评估差异无统计学意义(P>0.05)。结论中药熏蒸与体外冲击波两种疗法的有机结合,对于缓解髋关节撞击综合征的局部疼痛、改善髋关节功能活动、降低血清炎症因子水平有明显效果,同时能有效避免口服药物的不良反应和手术造成的损伤,对髋关节撞击综合征疗效显著,值得临床推广应用。

关键词: 髋关节撞击综合征, 中药熏蒸, 体外冲击波, 疗效, 血清炎症因子, 不良反应

Abstract: Objective To explore the clinical efficacy of traditional Chinese medicine(TCM)fumigation combined with extracorporeal shock wave in the treatment of femoroacetabular impingement syndrome(FAI)and the effects on the level of serum inflammatory factors. Methods A total of 72 patients with FAI treated in the Outpatient and Inpatient Departments during Dec. 2019 and Sep. 2021 were divided into the observation group and control group randomly, with 36 cases in either group. The control group was treated with extracorporeal shock wave of divergent mode, pressure 2.0-3.0 bar, 3 000-4 000 times once every 3 days. The observation group received the same treatment as the control group, plus fumigation once a day for 30 min. Both groups were treated for 30 days. The visual analogue score(VAS), Harris hip score(HHS), serum matrix metalloproteinase-13(MMP-13), interleukin-1β(IL-1β)level, quality of life and safety of treatment before treatment and 4 weeks after treatment were analyzed with SPSS 26.0 software to compared the clinical efficacy. Results After treatment, the total effective rate of the observation group was higher than that of the control group(P<0.05). The VAS and HHS scores of the two groups were improved compared with those before treatmnt, and the improvement in VAS and HHS of the observation group was more obvious than that of the control group(P<0.05). The levels of MMP-13 and IL-1β in both groups were lower than those before treatment, and those in the observation group were lower than those in the control group(P<0.05). The quality of life score of both groups was higher after treatment, and that of the observation group after treatment was higher than that of the control group(P<0.05). There was no statistical significance in the treatment safety between the two groups(P>0.05). Conclusion The combination of TCM fumigation and extracorporeal shock wave has a significant effect on alleviating the local pain of FAI, improving the functional activities of hip joint and reducing the levels of serum inflammatory factors. Meanwhile, it can effectively avoid the adverse reactions of oral drugs and damage caused by surgery. Therefore, it is worthy of clinical application.

Key words: Femoroacetabular impingement syndrome, Traditional Chinese medicine fumigation, Extracorporeal shock wave, Curative effect, Serum inflammatory factors, Adverse reactions

中图分类号:

R274.9

孙继业,王紫欧,孙晓伟,李洪涛. 中药熏蒸联合体外冲击波对72例髋关节撞击综合征临床疗效、血清炎症因子水平的影响[J]. 山东大学学报 (医学版), 2022, 60(4): 76-81.

SUN Jiye, WANG Ziou, SUN Xiaowei, LI Hongtao. Effects of traditional Chinese medicine fumigation combined with extracorporeal shock wave therapy on 72 cases of femoroacetabular impingement syndrome and serum inflammatory factor[J]. Journal of Shandong University (Health Sciences), 2022, 60(4): 76-81.

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