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山东大学学报 (医学版) ›› 2022, Vol. 60 ›› Issue (1): 93-100.doi: 10.6040/j.issn.1671-7554.0.2021.0913

• 公共卫生与管理学 • 上一篇    下一篇

山东省农村地区多重慢病患者多重用药现状及影响因素分析

王春霞1,2,贺梦璐1,2,王海鹏1,2,李慧1,2   

  1. 1. 山东大学齐鲁医学院公共卫生学院卫生管理与政策研究中心, 山东 济南 250012;2. 国家卫生健康委员会卫生经济与政策研究重点实验室(山东大学), 山东 济南 250012
  • 发布日期:2022-01-08
  • 通讯作者: 李慧. E-mail:huili@sdu.edu.cn
  • 基金资助:
    美国中华医学基金会资助项目(18-298)

Prevalence and influencing factors of polypharmacy in multimorbidity patients in rural areas of Shandong Province

WANG Chunxia1,2, HE Menglu1,2, WANG Haipeng1,2, LI Hui1,2   

  1. 1. Centre for Health Management and Policy Research, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan 250012, Shandong, China;
    2. NHC Key Lab of Health Economics and Policy Research (Shandong University), Jinan 250012, Shandong, China
  • Published:2022-01-08

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摘要： 目的 分析山东省农村地区多重慢病患者的患病情况,用药种类、数量和合理性状况,并探讨其影响因素。 方法 2019年11月采用多阶段随机抽样的方法选取山东省16个村531名多重慢病患者进行问卷调查,描述患者患病情况、用药数量及类型;依据《中国老年人潜在不适当用药判断标准(2017年版)》评价潜在不适当用药情况;采用回归分析法进行影响因素分析。 结果 多重慢病患者合并疾病(2.88±0.95)种;平均用药(3.64±1.65)种,多重用药患者占24.5%,以心血管及内分泌系统用药为主;共审查出312位(58.8%)患者存在潜在不适当用药;Logistic回归结果显示性别、患病数量、自评健康状况是多重用药的影响因素(P<0.05),性别、服药种类数是潜在不适当用药的影响因素(P<0.05)。 结论 农村多重慢病患者潜在不适当用药比例较高,强化农村多重慢病的综合用药管理非常关键。

关键词: 多重慢病, 多重用药, 潜在不适当用药, 现状, 影响因素

Abstract: Objective To analyze the disease prevalence of multimorbidity and the types, quantity and rationality of polypharmacy in rural areas of Shandong Province, and to explore the influencing factors. Methods In November 2019, 531 patients with multimorbidity from 16 villages in Shandong Province were selected by multistage random sampling method for questionnaire survey to describe the disease situation, medication quantity and type of the patients. Potential inappropriate medication was evaluated according to the Criteria of Potentially Inappropriate Medications for Older Adults in China(2017 edition). Regression analysis was used to analyze the influencing factors. Results Multimorbidity patients complicated with diseases(2.88±0.95)species; the average number of medication was(3.64±1.65)species, and the polypharmacy patients accounted for 24.5%, mainly cardiovascular and endocrine system medication; potential inappropriate medication accounted for 312 cases(58.8%). Logistic regression results showed that gender, number of chronic diseases, self-rated health status were the influencing factors for polypharmacy(P<0.05), and gender and number of medications were the influencing factors for potential inappropriate medication(P<0.05). Conclusion The proportion of potential inappropriate medication in rural patients with multimorbidity is high. It is necessary to strengthen the comprehensive medication management of rural patients with multimorbidity.

Key words: Multimorbidity, Polypharmacy, Potential inappropriate medication, Prevalence, Influencing factor

中图分类号: 

  • R181.3+5
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