山东大学学报(医学版) ›› 2017, Vol. 55 ›› Issue (7): 110-114.doi: 10.6040/j.issn.1671-7554.0.2016.1358
王蒙1,王澂1,张迎春1,李杰2, 孙霄2,时丹丹2,商蒙蒙2,宁松2
WANG Meng1, WANG Cheng1, ZHANG Yingchun1, LI Jie2, SUN Xiao2, SHI Dandan2, SHANG Mengmeng2, NING Song2
摘要: 目的 评估超声波声学特性、结石表面形貌及机器设置条件在闪烁伪像形成中的价值。 方法 应用砂纸及泌尿系结石分别构建体外实验模型,砂纸模型中通过调节IU22声学功率参数(包括机械指数及声波入射角度)改变超声波特性,结石模型分别按照表面粗糙度差异进行结石分组(包括粗糙组,中度粗糙组与光滑组),然后选取两种不同机器设置条件(默认设置与优化设置)进行闪烁伪像成像,应用配对t检验分析比较砂纸模型中垂直辐射组与斜方辐射组闪烁伪像差异;应用重复测量设计的方差分析比较结石模型中不同机器设置条件下不同表面粗糙度结石组间闪烁伪像强度差异;通过线性回归分析分别对砂纸模型中机械指数、结石模型中不同结石粗糙度与闪烁伪像强度之间进行相关性分析。 结果 在砂纸模型中,机械指数与闪烁伪像强度存在显著正相关(r=0.938, P<0.001),斜方辐射组闪烁伪像强度较垂直辐射组明显减弱(P<0.05);泌尿系结石模型中,不同表面粗糙度泌尿系结石的闪烁伪像强度组间差异有统计学意义且其两个影响因素(表面粗糙度与机器设置条件)存在交互作用(P<0.001),相同表面粗糙度的泌尿系结石中的闪烁伪像强度在机器优化设置条件下均明显强于默认设置条件(P<0.001),而在相同机器设置条件下不同组间结石闪烁伪像强度与其表面粗糙程度呈明显正相关(r默认设置条件=0.80, r优化设置条件=0.83, P<0.001)。 结论 砂纸模型及泌尿系结石模型均显示闪烁伪像形成受超声波声学特性、结石表面粗糙度及机器设置条件的共同影响,了解各种相关因素的作用可提升其临床应用价值。
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