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山东大学学报 (医学版) ›› 2018, Vol. 56 ›› Issue (11): 68-75.doi: 10.6040/j.issn.1671-7554.0.2018.538

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石家庄市大气颗粒污染物浓度对儿童呼吸系统疾病门诊量的影响

陈浪,赵川,陈凤格,白萍   

  1. 1.华北理工大学公共卫生学院预防医学系, 河北 唐山 063210;2.石家庄市疾病预防控制中心环境所, 河北 石家庄 050011
  • 发布日期:2022-09-27
  • 通讯作者: 赵川. E-mail:article9999@163.com
  • 基金资助:
    国家科技基础资源调查专项(2017FY101300);河北省自然科学基金青年基金(C2016106056);石家庄市科学技术研究与发展指导计划(171462073)

Effect of airborne particulates concentration on outpatient visits of respiratory diseases among children in Shijiazhuang City

CHEN Lang, ZHAO Chuan, CHEN Fengge, BAI Ping   

  1. 1. Department of Preventive Medicine, North China University of Science and Technology, Tangshan 063210, Hebei, China;
    2. Institute of Environmental Health, Shijiazhuang Center for Disease Control and Prevention, Shijiazhuang 050011, Hebei, China
  • Published:2022-09-27

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摘要： 目的 探讨石家庄市大气颗粒物PM10和PM2.5对儿童呼吸系统疾病门诊量的影响。 方法 收集2013年1月1日至2017年12月31日石家庄市大气颗粒物PM10和PM2.5日均质量浓度(以下简称“浓度”)、气象因素(日均温度、日均相对湿度)以及每日门诊数据并进行描述。采用广义相加模型的时间序列分析方法分析儿童呼吸系统疾病门诊量与PM10和PM2.5浓度的关系。 结果 石家庄市2013~2017年PM10、PM2.5的平均浓度分别为195.03 μg/m3和107.13 μg/m3。时间序列分析表明,PM10(lag0)、PM2.5(lag0)浓度每升高10 μg/m3,儿童呼吸系统疾病门诊量分别增加0.11%(95%CI:0.07%~0.16%)和0.22%(95%CI:0.15%~0.28%);调整气态污染物O3/SO2/NO2后,PM10对呼吸系统疾病门诊量的效应消失,PM2.5的健康效应略微下降。 结论 石家庄市PM2.5和PM10浓度升高可能导致儿童呼吸系统疾病门诊量增加,提示有必要加强空气污染的治理控制措施,保护儿童健康。

关键词: 空气污染, 呼吸系统疾病, 日门诊量, 儿童, 时间序列分析

Abstract: Objective To investigate the effect of the concentrations of airborne particulates PM10 and PM2.5 on daily outpatient visits of respiratory diseases among children in Shijiazhuang City. Methods The data of PM10 and PM2.5 concentrations, meteorological factors(daily average temperature and relative humidity), and daily outpatient visits of respiratory diseases among children during 2013 and 2017 were collected and described in Shijiazhuang City. A time series analysis using a generalized addictive model(GAM)was applied to evaluate the association between pediatric outpatient visits for respiratory diseases and PM10 and PM2.5 exposure. Results The average concentrations of PM10 and PM2.5 in Shijiazhuang City were respective 195.03 and 107.13 μg/m3. Time series analysis showed that an increase of 10 μg/m3 of PM10 and PM2.5 could increase the risk of outpatient visits of respiratory diseases by 0.11%(95%CI: 0.07%-0.16%)and 0.22%(95%CI: 0.15%-0.28%), respectively. After adjusting the gaseous pollutant O3/SO2/NO2, the acute health effects of PM10 disappeared and the health effects of PM2.5 declined slightly. Conclusion The increase of PM10 and PM2.5 concentrations may increase outpatient visits of respiratory diseases in children, recommending the relevant departments should strengthen control of air pollution and protect childrens health.

Key words: Air pollution, Respiratory disease, Daily outpatient visits, Children, Time series analysis

中图分类号: 

  • R122.7
[1] 陈仁杰,张金良,阚海东,等.中国大气污染与肺癌关系的流行病学研究回顾[J].卫生研究, 2011, 40(2): 243-245.
[2] 姜静.浅谈大气污染状况与防治措施[C] // 中华环保联合会.第九届环境与发展论坛论文集. 中华环保联合会, 2013.
[3] 殷永文,程金平,段玉森,等.上海市霾期间PM2.5、PM10污染与呼吸科、儿呼吸科门诊人数的相关分析[J].环境科学, 2011, 32(7): 1894-1898. YIN Yongwen, CHENG Jinping, DUAN Yusen, et al. Correlation analysis between the PM2.5, PM10 which were taken in the hazy day and the number of outpatient about breathing sections, breathing sections of pediatrics in Shanghai[J]. Environmental Science, 2011, 32(7): 1894-1898.
[4] 涂宏.南昌市城区PM2.5的污染特征及其与儿童健康关系的研究[D].南昌:南昌大学, 2016.
[5] 谷少华,贾红英,李萌萌,等.济南市空气污染对呼吸系统疾病门诊量的影响[J].环境与健康杂志, 2015, 32(2): 95-98. GU Shaohua, JIA Hongying, LI Mengmeng, et al. Effects of air pollution on hospital visits for respiratory diseases in Jinan City[J]. Journal of Environment and Health, 2015, 32(2): 95-98.
[6] 刘波,刘晓峰,杨冬梅,等.北京市通州区空气污染与医院门诊量关系初探[J].首都公共卫生, 2017, 11(5): 212-216. LIU Bo, LIU Xiaofeng, YANG Dongmei, et al. Study on the relationship between air pollution and outpatient visits in Tongzhou District of Beijing from 2015 to 2016[J]. Capital Journal of Public Health, 2017, 11(5): 212-216.
[7] 张江华,郭常义,许慧慧,等.上海市大气污染与某医院呼吸系统疾病门诊量关系的时间序列研究[J].环境与职业医学, 2014, 31(11): 846-851. ZHANG Jianghua, GUO Changyi, XU Huihui, et al. Time-Series analysis on association between air pollution and outpatient visits for respiratory diseases in a hospital in Shanghai[J]. Journal of Environmental & Occupational Medicine, 2014, 31(11): 846-851.
[8] 符文华,孙百军,齐宏业,等.沈阳市某社区医院儿科门诊量与空气质量及气象因素的关系[J].职业与健康, 2017, 33(1): 105-109. FU Wenhua, SUN Baijun, QI Hongye, et al. Relationship between pediatric outpatient volume in a community hospital in Shenyang and air quality and meteorological factors[J]. Occupation and Health, 2017, 33(1): 105-109.
[9] 张衍燊,马国霞,於方,等.2013年1月灰霾污染事件期间京津冀地区PM2.5污染的人体健康损害评估[J].中华医学杂志, 2013, 93(34): 2707-2710. ZHANG Yanshen, MA Guoxia, YU Fang, et al. Health damage assessment due to PM2.5 exposure during haze pollution events in Beijing-Tianjin-Hebei region in January 2013[J]. National Medical Journal of China, 2013, 93(34): 2707-2710.
[10] 张迪,李青山,吕文峰,等.雾霾天气污染现状与分析[J].环境保护前沿, 2013, 1(3): 25-28.
[11] 张文彤,闫洁. SPSS 统计分析基础教程[M].北京:高等教育出版社, 2005: 235-237.
[12] 张云权,朱耀辉,李存禄,等.广义相加模型在R软件中的实现[J].中国卫生统计, 2015, 32(6): 1373-1075.
[13] 李国星,陶辉,刘利群,等. PM10与表观温度交互作用对北京市某医院呼吸系统疾病急诊的影响[J].环境与健康杂志, 2012, 29(6): 483-486. LI Guoxing, TAO Hui, LIU Liqun, et al. Interaction between inhalable particulate matter and apparent temperature on respiratory emergency room visits of a hospital in Beijing[J]. Journal of Environment and Health, 2012, 29(6): 483-486.
[14] Gasparrini A. Modeling exposure-lag-response associations with distributed lag non-linear models[J]. Stat Med, 2014, 33(5): 881-899.
[15] 陈浪,赵川,关铭洋,等.石家庄市大气颗粒物污染物浓度与居民死亡率的时间序列分析[J].中华疾病控制杂志, 2018, 22(3): 272-277. CHEN Lang, ZHAO Chuan, GUAN Mingyang, et al. Time-series analysis of the relationship between particulate matter and mortality in Shijiazhuang[J]. Chinese Journal of Disease Control & Prevention, 2018, 22(3): 272-277.
[16] Khaniabadi YO, Goudarzi G, Daryanoosh SM, et al. Exposure to PM10, NO2, and O3 and impacts on human health[J]. Environ Sci Pollut Res Int, 2017, 24(3): 2781-2789.
[17] Shahi AM, Omraninava A, Goli M, et al. The effects of air pollution on cardiovascular and respiratory causes of emergency admission[J]. Emerg(Tehran), 2014, 2(3): 107-114.
[18] 张永利,刘卫艳,陈树旭,等.大气污染物与学龄儿童呼吸系统疾病的关联研究[J].上海预防医学, 2017, 29(11): 847-849. ZHANG Yongli, LIU Weiyan, CHEN Shuxu, et al. Effect of air pollution on respiratory health of school children[J]. Shanghai Journal of Preventive Medicine, 2017, 29(11): 847-849.
[19] 王艳,张宜生,李欣鹏,等.济南城区空气污染对呼吸道疾病门诊量的影响[J].中国环境科学, 2008, 28(6): 571-576. WANG Yan, ZHANG Yisheng, LI Xinpeng, et al. The effect of air pollution on hospital visits for respiratory symptoms in urban areas of Jinan[J]. China Environmental Science, 2008, 28(6): 571-576.
[20] 刘准,陈丹,霍细香,等.武汉市大气污染物水平与儿童呼吸道疾病门诊量的滞后效应分析[J]. 环境与职业医学, 2018, 35(2): 124-130. LIU Zhun, CHEN Dan, HUO Xixiang, et al. Lag effects of air pollutant levels on pediatric respiratory disease outpatient visits in Wuhan[J]. Journal of Environmental & Occupational Medicine, 2018, 35(2): 124-130.
[21] 张媛媛,刘宗伟,李文龙,等. 2016年潍坊市空气污染对儿童呼吸系统疾病门诊量的影响[J]. 环境与职业医学, 2018, 35(1): 24-28. ZHANG Yuanyuan, LIU Zongwei, LI Wenlong, et al. Effects of air pollution on outpatient visits of respiratory diseases among children in Weifang in 2016[J]. Journal of Environmental & Occupational Medicine, 2018, 35(1): 24-28.
[22] 宋杰,徐东群,赵伟,等.华北某城市大气颗粒物浓度对神经系统疾病急救人次的急性影响[J].卫生研究, 2016, 45(6): 932-937. SONG Jie, XU Dongqun, ZHAO Wei, et al. Acute effects of particulate matter pollution on daily emergency ambulance dispatches due to neurological diseases in one haze polluted city of the North China[J]. Journal of Hygiene Research, 2016, 45(6): 932-937.
[23] Touloumi G, Atkinson R, Tertre AL, et al. Analysis of health outcome time series data in epidemiological study[J]. Environ Metrics, 2004, 15(2): 101-117.
[24] Bi X, Feng Y, Wu J, et al. Source apportionment of PM in six cities of northern China[J]. Atmospheric Environment, 2007, 41(5): 903-912.
[25] 彭朝琼,余淑苑,张振,等.深圳市大气PM10浓度对呼吸系统疾病日门诊量的影响[J].卫生研究, 2011, 40(4): 485-488. PENG Zhaoqiong, YU Shuyuan, ZHANG Zhen, et al. Effect of ambient air PM10 concentration on the hospital outpatient visit of respiratory diseases in Shenzhen City[J]. Journal of Hygiene Research, 2011, 40(4): 485-488.
[26] 赵梦娇,耿兴义,崔亮亮,等.济南市2013-2015年某综合医院呼吸系统疾病就诊人次与大气颗粒物PM10、PM2.5关系的时间序列研究[J].中华流行病学杂志, 2017, 38(3): 374-377. ZHAO Mengjiao, GENG Xingyi, CUI Liangliang, et al. Association between ambient PM10/PM2.5 concentration and outpatient department visits due to respiratory disease in a hospital in Jinan, 2013-2015: a time series analysis[J]. Chinese Journal of Epidemiology, 2017, 38(3): 374-377.
[27] 王玮,叶慧海,金大善,等.交通来源颗粒物及其无机成分污染特征的研究[J].环境科学研究, 2001, 14(4): 27-31. WANG Wei, YE Huihai, KIM Daeseon, et al. Study on characteristics of particulate matters and their inorganic compositions from traffic sources[J]. Research of Environmental Sciences, 2001, 14(4): 27-31.
[28] Zhai YB, Liu XT, Chen HM, et al. Source identification and potential ecological risk assessment of heavy metals in PM2.5 from Changsha[J]. Sci Total Environ, 2014, 493(1): 109-115.
[29] 杨克敌,郑玉建.环境卫生学[M].北京:人民卫生出版社, 2013: 95-96.
[30] Mills IC, Atkinson RW, Anderson HR, et al. Distinguishing the associations between daily mortality and hospital admissions and nitrogen dioxide from those of particulate matter: a systematic review and meta-analysis[J]. BMJ Open, 2016, 6(7): e010751. doi: 10.1136/bmjopen-2015-010751.
[31] Sarnat JA, Schwartz J, Catalano PJ, et al. Gaseous pollutants in particulate matter epidemiology: confounders or surrogates[J]. Environ Health Perspect, 2011, 9(10): 1053-1061.
[32] 梁志江,马远珠,缪华章,等.广州地区空气污染对儿童呼吸系统疾病就诊人次的影响研究[J].环境与健康杂志, 2015, 3(6): 481-484. LIANG Zhijiang, MA Yuanzhu, MIAO Huazhang, et al. Effect of air pollution on outpatient visits of respiratory diseases among children in Guangzhou[J]. Journal of Environment and Health, 2015, 3(6): 481-484.
[33] Li Z, Wen Q, Zhang R, et al. Sources, health effects and control strategies of indoor fine particulate matter PM2.5: a review[J]. Sci Total Environ, 2017, 86: 610-622. doi: 10.1016/j.scitotenv.2017.02.029.
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