您的位置：山东大学 -> 科技期刊社 -> 《山东大学学报（医学版）》

山东大学学报（医学版） ›› 2015, Vol. 53 ›› Issue (9): 19-23.doi: 10.6040/j.issn.1671-7554.0.2014.931

• 基础医学 • 上一篇    下一篇

泌尿系结石化学成分对超声声影强弱的影响

刘青1, 商蒙蒙1, 孙霄1, 李杰1, 杨杰2, 时丹丹1, 宁松1   

  1. 1. 山东大学齐鲁医院超声科, 山东 济南 250012;
    2. 山东省荣军总医院超声科, 山东 济南 250013
  • 收稿日期:2014-12-09 出版日期:2015-09-10 发布日期:2015-09-10
  • 通讯作者: 李杰。E-mail:jieli301@163.com E-mail:jieli301@163.com
  • 基金资助:
    山东大学基本科研业务专项资金[山东大学齐鲁医院科研基金(2015QLMS39)]

Effects of chemical composition of urinary stones on their acoustic shadowing

LIU Qing1, SHANG Mengmeng1, SUN Xiao1, LI Jie1, YANG Jie2, SHI Dandan1, NING Song1   

  1. 1. Department of Ultrasound, Qilu Hospital of Shandong University, Jinan 250012, Shandong, China;
    2. Department of Ultrasound, Rongjun General Hospital of Shandong, Jinan 250013, Shandong, China
  • Received:2014-12-09 Online:2015-09-10 Published:2015-09-10
  • Contact: 李杰。E-mail:jieli301@163.com E-mail:jieli301@163.com

PDF (PC)

492

摘要： 目的 定量研究结石化学成分与超声声影的关系。方法 制备一水草酸钙、羟基磷灰石、胱氨酸和尿酸结石模型,包埋于猪肾中进行超声扫查及CT扫描,记录各结石模型所产生声影的对比噪声比(C/N)及CT值,并行统计分析。结果 所有结石均表现为强回声伴后方声影征象,声影C/N值大小为1.01~3.74,平均为2.17;以结石化学成分分组,超声声影C/N值及CT值由大到小排列依次为羟基磷灰石、一水草酸钙、胱氨酸、尿酸,差异有统计学意义(P均<0.001);声影C/N值与CT值呈正相关(r=0.942, P<0.001)。结论 结石所产生的声影强弱程度与其化学成分密切相关,且声影的强弱趋势与CT值大小趋势一致;可通过声影的强弱程度对结石化学成分进行初步预测。

关键词: 声影, 泌尿系结石, 化学成分, 电子计算机断层扫描, 超声

Abstract: Objective To quantitatively analyze the association between chemical composition of urinary stones and acoustic shadowing. Methods Calcium oxalate monohydrate, hydroxyapatite, cystine, and uric acid stone phantoms were prepared and embedded in porcine kidneys for ultrasound and CT scanning. The contrast-to-noise ratio (C/N) of acoustic shadowing and Hounsfield unit were recorded. All data obtained were analyzed statistically. Results All stones demonstrated high acoustic echo with shadowing. Of all stone phantoms, C/N ratio was 1.01-3.74, 2.17 in average. The hydrocyapatite stones displayed the strongest C/N ratio of acoustic shadowing and Hounsfield unit, followed by calcium oxalate monohydrate, cystine and uric acid stones (all P<0.001). The C/N ratio was significantly correlated with the Hounsfield unit (r=0.942,P<0.001) for all stone phantoms. Conclusion Stones with different chemical compositions have different acoustic shadowing, but the clarity of acoustic shadowing has the same trend with the Hounsfield unit, and acoustic shadowing can be used to predict the chemical compositions.

Key words: Chemical composition, Ultrasonography, Urinary stone, Computed Tomography, Acoustic shadowing

中图分类号: 

  • R816.7
[1] 吴在德, 吴肈汉. 外科学[M]. 7版. 北京:人民卫生出版社, 2011: 679-681.
[2] Shabana W, Bude RO, Rubin JM. Comparison between color Doppler twinkling artifact and acoustic shadowing for renal calculus detection: an in vitro study[J]. Ultrasound Med Biol, 2009, 35(2): 339-350.
[3] Ather MH, Jafri AH, Sulaiman MN. Diagnostic accuracy of ultrasonography compared to unenhanced CT for stone and obstruction in patients with renal failure[J]. BMC Med Imaging, 2004, 4(1): 2.
[4] Song X, Pogue BW, Jiang S, et al. Automated region detection based on the contrast-to-noise ratio in near-infrared tomography[J]. Appl Opt, 2004, 43(5): 1053-1062.
[5] Ogura A, Maeda F, Miyai A, et al. Accuracy of contrast-to noise ratio measurement for magnetic resonance clinical images[J]. Nihon Hoshasen Gijutsu Gakkai Zasshi, 2004, 60(11): 1543-1549.
[6] Techavipoo U, Varghese T. Improvements in elastographic contrast-to-noise ratio using spatial-angular compounding[J]. Ultrasound Med Biol, 2005, 31(4): 529-536.
[7] Moe OW. Kidney stones: pathophysiology and medical management[J]. The lancet, 2006, 367(9507): 333-344.
[8] 孙西钊, 孙则禹, 叶章群. 结石理化因素对冲击波碎石的影响及对策[J]. 临床泌尿外科杂志, 2000, 15(11): 485-487. SUN Xizhao, SUN Zeyu, YE Zhangqun.The influence and measurements of physical and chemical factors of stones on shock-wave lithotripsy[J]. Journal of Clinical Urology, 2000, 15(11): 485-487.
[9] King W 3rd, Kimme-Smith C, Winter J. Renal stone shadowing:an investigation of contributing factors[J]. Radiology, 1985, 154(1): 191-196.
[10] 周永昌, 郭万学. 超声医学[M]. 6版. 北京: 人民军医出版社, 2013: 25.
[11] Rubin JM, Alder RS, Bude RO, et al. Clean and dirty shadowing at US: a reappraisal[J]. Radiology, 1991, 181(1): 231-236.
[12] 杨琪放, 张挽时, 孟利民, 等. 双源CT双能量成像对泌尿系结石成分分析的初步研究[J]. 中华放射学杂志, 2011, 45(2): 133-137. YANG Qifang, ZHANG Wanshi, MENG Limin, et al. Dual-source dual-energy CT for the differentiation of urinary stone composition: preliminary study[J]. Chin J Radiol, 2011, 45(2): 133-137.
[13] 李小虎, 余永强, 王万勤, 等. CT能谱成像对肾结石成分分析的初步研究[J]. 中华放射学杂志, 2011, 45(12): 1216-1219. LI Xiaohu, YU Yongqiang, WANG Wanqin, et al. Spectral CT imaging in the evaluation of composition of kidney stones[J]. Chin J Radiol, 2011, 45(12): 1216-1219.
[14] Westphalen AC, Hsia RY, Maselli JH, et al. Radiological imaging of patients with suspected urinary tract stones: national trends, diagnoses, and predictors[J]. Acad Emerg Med, 2011, 18(7): 699-707.
[15] Kokorowski PJ, Hubert K, Nelson CP. Evaluation of pediatric nephrolithiasis[J]. Indian J Urol, 2010, 26(4): 531-535.
[16] Kenny JE, Goldfard DS. Update on the pathophysiology and management of uric acid renal stones[J]. Curr Rheumatol Rep, 2010, 12(2): 125-129.
[1] 徐平 于国放 李霞. 不同类型甲状腺上动脉PSV对Graves病与桥本氏甲状腺炎鉴别诊断的价值[J]. 山东大学学报(医学版), 2209, 47(6): 62-64.
[2] 王艳萍,王玉波,董林,唐娜,徐晴晴,郭广君,郭时金,杨丽梅,徐子贤,张浩天,张文勇,徐倩倩. 响应面优化超声辅助低共熔溶剂提取惠白菊总黄酮工艺[J]. 山东大学学报 (医学版), 2026, 64(5): 29-41.
[3] 李懿原,马珊,李爱华,龙飞. 超声支气管镜引导下碘-125粒子植入治疗肺癌中央区淋巴结转移[J]. 山东大学学报 (医学版), 2025, 63(12): 26-34.
[4] 董向毅,刘昕,刘欣欣,徐亚瑄,赵琳丽,陶国伟. 盆腔深部子宫内膜异位症的超声评价[J]. 山东大学学报 (医学版), 2025, 63(10): 34-42.
[5] 孙婧,杨瑞敏,王聪,张月,罗兵. 基于术前超声、炎症指标及超声影像组学联合模型预测乳腺癌腋窝淋巴结转移[J]. 山东大学学报 (医学版), 2025, 63(1): 73-80.
[6] 卢晓颂,杨瑞敏,王义成,周海丰,罗兵,李晓宇,李娜娜. 含瘤周组织的超声影像组学在鉴别乳腺结节良恶性中的价值[J]. 山东大学学报 (医学版), 2025, 63(1): 90-98.
[7] 冯昌,郭岩,赵杰,赵鑫. 加速康复外科理念下超声引导区域阻滞在骨科手术中的研究进展[J]. 山东大学学报 (医学版), 2024, 62(10): 26-35.
[8] 李红梅,蔡敏,周立,姚欣雨,刘力. 不同膈肌超声功能指标在腹部手术后肺部并发症中的预测价值[J]. 山东大学学报 (医学版), 2024, 62(10): 115-124.
[9] 刘永国,苏文桂,孙国宝,张程榕,张立刚,祝增军. CT阴性结石误诊为输尿管肿瘤1例[J]. 山东大学学报 (医学版), 2024, 62(1): 120-124.
[10] 于婷,李媛,吴梅. 超声诊断羊膜带综合征并胎头离断1例[J]. 山东大学学报 (医学版), 2023, 61(8): 122-124.
[11] 陈天杰,张晓华,王瑞霞,赵淑磊. 超声内镜引导下细针穿刺抽吸术诊断胰腺淋巴管瘤合并术后感染1例[J]. 山东大学学报 (医学版), 2023, 61(7): 121-124.
[12] 吴磊丽,蔡华丽,孙德胜,魏蔚霞. 超声引导穿刺硬化术联合地诺孕素治疗卵巢子宫内膜异位囊肿的疗效[J]. 山东大学学报 (医学版), 2023, 61(6): 65-69.
[13] 王智璠,林小仙,阴佳璐,王东亮,王姝麒. 不同炖煮温度燕窝次生代谢化学成分组学[J]. 山东大学学报 (医学版), 2023, 61(4): 10-17.
[14] 徐帅娅,罗芳琼,巴晨曦,张鑫茹,马喆. 多模态超声对70例BI-RADS 4类乳腺病变的诊断价值[J]. 山东大学学报 (医学版), 2023, 61(2): 95-101.
[15] 盛璇,刘纪锋,张歌,尹虹,宋琳琳,王雯. 产前超声诊断胎儿肢根型点状软骨发育不良合并白内障1例并文献复习[J]. 山东大学学报 (医学版), 2023, 61(11): 121-124.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
No Suggested Reading articles found!
版权所有 © 2018 《山东大学学报(医学版)》编辑部　
地址:山东大学科技期刊社（济南市历城区山大南路27号山东大学中心校区明德楼B座721室） 电话: 0531-88366918 E-mail: xbyxb@sdu.edu.cn
本系统由北京玛格泰克科技发展有限公司设计开发