知觉压力在维持性血液透析患者正念水平与失志综合征间的中介效应

doi:10.6040/j.issn.1671-7554.0.2025.0819

Abstract

Abstract: Objective To investigate the current status and influencing factors of demoralization syndrome in maintenance hemodialysis(MHD)patients, and analyze the mediating effect of perceived stress between mindfulness and demoralization syndrome. Methods A cross-sectional survey was conducted among 350 MHD patients from two tertiary hospitals in Yantai, China, from August to September 2024. Data were collected via structured questionnaires including general information, the Demoralization Syndrome Scale-II(DSS-II), the Perceived Stress Scale(PSS), and the Mindful Attention Awareness Scale(MAAS). Statistical analyses were performed using univariate analysis, Pearson or Spearman correlation analysis, multiple linear regression analysis, and the Bootstrap mediation analysis. Results The median score of demoralization syndrome in MHD patients was 9 points, and the proportion of patients with moderate to severe demoralization syndrome was 47.0%(41.8% for moderate and 5.2% for severe). The score of mindfulness level was(60.12±12.60), and the score of perceived stress was(26.71±7.15). Perceived stress was positively correlated with demoralization syndrome(r_s=0.783, P<0.001), while mindfulness level was negatively correlated with demoralization syndrome(r_s=-0.699, P<0.001). Mindfulness level(β=-0.249, P<0.001)negatively predicted demoralization syndrome, while perceived stress(β=0.550, P<0.001)and unemployment(β=0.105, P=0.012)positively predicted demoralization syndrome. The total effect of mindfulness level on demoralization syndrome was -0.29(P<0.001), including a direct effect of -0.12(41.38%)and a mediating effect of perceived stress between mindfulness level and demoralization syndrome of -0.17(58.62%). Conclusion Among MHD patients, the incidence proportion of moderate to severe demoralization syndrome is relatively high. Perceived stress plays a partial mediating role between patients mindfulness level and demoralization syndrome.

Key words: Maintenance hemodialysis, Demoralization syndrome, Perceived stress, Mindfulness

CLC Number:

R473.5

ZHENG Jinai, WANG Yanmei, QU Yan, LI Liwei, LIU Yong, ZHANG Yuan. Mediating effect of perceived stress between mindfulness and demoralization syndrome in maintenance hemodialysis patients[J].Journal of Shandong University (Health Sciences), 2026, 64(4): 109-116.

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Mediating effect of perceived stress between mindfulness and demoralization syndrome in maintenance hemodialysis patients

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