Abstract:

Objective   To evaluate the clinical value of the radial artery blood flow for predicting pre-eclampsia in gravidas, and to accurately identify high-risk pregnant women, and to early predict the incidence of pre-eclampsia. Methods   Data from 10433 pregnant women at 16-36 weeks of gestation who were free of hypertension, diabetes mellitus, renal disease, cardiovascular disease and other complications in prenatal screening were analyzed by the case-control study. These pregnant women were randomly divided into the study group and the control group. The pregnant women in the study group were monitored for the radial artery flow chart by the hypertensive disorder in the pregnancy monitoring system. They were examined at 4-week intervals. For the pregnant women positive with hypertensive disorders by the pregnancy monitoring system,  the measurement was repeated every 2 weeks and intervention was applied. The pregnant women in the control group were given interventions until pre-eclampsia symptoms appeared. All pregnant women were followed-up until after delivery. The severity and the incidence of preeclampsia and Intrauterine Growth Retardation(IUGR) in the two groups were compared. Results   The incidences of pre-eclampsia and eclampsia in the study group were 11.2% and 0.11%, while the incidences were 13.5% and 0.29% (P<0.05) in the control group. The rates of IUGR in the study and control groups were 5.11% and 7.06%(χ2=15.38，P<0.01). The severity of pre-eclampsia in the control group was significantly higher compared to the study group (P<0.05). The sensitivity of the MP monitoring system in predicting preeclampsia was different at different gestational ages, and the rate of the pre-eclampsia positive prediction coincidence increased with the gestational age. Conclusions   Applying the pregnancy monitoring system for hypertensive disorders to early predict pre-eclampsia, and giving interventions to pregnant women with positive -predictions, can significantly reduce the incidence of preeclampsia and prevent the development of severe disease and improve the maternal and perinatal infant outcome.

Key words: Pre-eclampsia; Radial artery flow chart; Prediction; Interference