腹膜透析患者残余肾功能下降与营养不良的关系

山东大学学报(医学版)

腹膜透析患者残余肾功能下降与营养不良的关系

范晓红¹,程李涛²,汪涛²,胡昭¹

1. 山东大学齐鲁医院肾内科, 济南 250012; 2. 北京大学第三医院肾内科, 北京 100083

收稿日期:2008-05-30 修回日期:1900-01-01 出版日期:2008-11-16 发布日期:2008-11-16
通讯作者: 胡昭

Relationship between loss of residual renal function and malnutrition in peritoneal dialysis patients

FAN Xiao-hong¹, CHENG Li-tao², WANG Tao², HU Zhao¹

1. Department of Nephrology, Qilu Hospital of Shandong University, Jinan 250012, China;
2. Department of Nephrology, Third Hospital of Peaking University, Beijing 100083, China

Received:2008-05-30 Revised:1900-01-01 Online:2008-11-16 Published:2008-11-16
Contact: HU Zhao

摘要/Abstract

摘要： 目的观察残余肾功能(RRF)下降对腹膜透析(PD)患者营养状况的影响。方法选取1年内肾小球滤过率下降≥50％的32名腹膜透析患者，以肾脏尿素与肌酐清除率评估患者RRF,同时密切随访血清白蛋白、饮食蛋白摄入(DPI)和主观综合营养评估情况。结果随患者RRF下降,尿量明显减少（P＜0.01)，血清白蛋白显著增加（P＜0.01),DPI增加明显。用主观综合评估(SGA)得到的营养不良发生率从开始透析时的62.5%降低到研究结束时的18.8%（P＜0.05)。结论腹膜透析患者RRF迅速下降并不一定导致DPI下降与营养状况恶化。

关键词: 腹膜透析, 营养不良, 残余肾功能

Abstract: Abstract: ObjectiveTo evaluate the effect of declining residual renal function (RRF) on peritoneal dialysis patients′ nutritional status. Method32 patients whose glomerular filtration rate (GFR) had decreased by more than 50% in one year were selected for the present analysis. Patients′ residual renal function was assessed by the average renal urea and creatinine clearances. Serum albumin(ALB), dietary protein intake(DPI) and subjective global assessment(SGA) were closely followed up. ResultsRRF was significantly decreased (P＜0.05) with a significant decrease of urine volume(P＜0.01), while serum ALB was significantly increased (P＜0.01), and also DPI was significantly increased. The prevalence of malnutrition(by SGA) was decreased from 62.5% at the start of dialysis to 18.8% at the end of this study(P＜0.05). ConclusionThe present study suggests that rapid decline of residual renal function in PD patients does not necessarily lead to a decreased dietary protein intake and deteriorated nutritional status.

Key words: Residual renal function, Malnutrition, Peritoneal dialysis

中图分类号:

R692.5

范晓红,程李涛,汪涛,胡昭 . 腹膜透析患者残余肾功能下降与营养不良的关系[J]. 山东大学学报(医学版), 2008, 46(11): 1080-1083.

FAN Xiao-hong,CHENG Li-tao,WANG Tao,HU Zhao. Relationship between loss of residual renal function and malnutrition in peritoneal dialysis patients[J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2008, 46(11): 1080-1083.

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