Abstract: To investigate the 3.0 Tesla magnetic resonance diffusionweighted images on focal malignant hepatic lesions. Methods: Magnetic resonance diffusionweighted imaging (DWI) was obtained in a total of 47 cases of focal malignant hepatic lesions including hepatocellular carcinoma (HCC), cholangiocellular carcinoma (CCC) and secondary tumors of liver pathologically. The characteristics of the DWI and apparent diffusion coefficient (ADC) values were analyzed. Results： The lesions with hyperintensity, heterogeneity or indistinct rim were in 46, 24, or 21 on DWI images, respectively. The ADC value of the HCC, CCC or secondary tumors of liver was (145.86±33.97)×10-3?mm2/s, (185±53.09)×10-3?mm2/s or (212.62±81.72)×10-3?mm2/s, respectively. There was a significant difference between liver tissue and the secondary tumor (t=3.202, P=0.011), and the ADC value was higher in HCC than that in CCC or in the secondary tumor (P＜0.05). Conclusion： DWI at 3.0 Tesla MR is conductive to accurate diagnosis of malignant lesions.

Key words: Liver neoplasms, Magnetic resonance imaging, Magnetic resonance