Abstract: Objective To study the quality of life (QOL) and influencing factors in patients with chronic rhinosinusitis and nasal polyps, and to evaluate the effects of the SF-36 questionnaire (Chinese version). Methods148 patients and 150 healthy controls were tested by SF-36 questionnaires. Correlation between the age, gender, case history, clinical classification, nasal endoscopic scores, CT scores and the QOL were analyzed. ResultsCompared with the control group， there was a significant impairment in six dimensions in the experimental group. The QOL had no significant differences between the two groups in age or gender. Case history was significantly negatively associated with the QOL. Clinical classification, nasal endoscopic scores and CT scores were correlated with the physiological health, but not correlated with the emotional health. The SF-36 questionnaire of the Chinese version was reliable and valid. Conclusions Chronic rhinosinusitis and nasal polyps have a negative impact on QOL. Case history plays a more important role in affecting the QOL. The SF-36 of the Chinese version is a valid outcome measure for patients with chronic rhinosinusitis and nasal polyps.

Key words: Rhinosinusitis, Nasal polyps, Quality of life, SF-36