JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES)

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Serum estradiol and threatened abortion in pregnancy of 4 to 8 weeks

GAO Qing1， WANG Mei-hong2， TANG Rong3   

  1. 1． Hospital of Maternal and Child Health, Jinan 250001, China; 2． Hospital of Shandong University, Jinan 250100, China;3．Center of Reproductive, Provincial Hospital Affiliated to Shandong University, Jinan 250021, China
  • Received:2008-05-11 Revised:1900-01-01 Online:2008-09-16 Published:2008-09-16
  • Contact: GAO Qing

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Abstract: To explore the relationship between serum estradiol and threatened abortion in women with pregnancy of 4 to 8 weeks. Methods259 pregnant women, who had conceived from 4 to 8 weeks were previously divided into 2 groups: 171 with normal pregnancy and 88 with threatened abortion, and then each group was divided into 5 subgroups based upon gestational age. Chemiluminescence reaction and dissociation enhanced lauthanide fluoroimmuno-assay were used to determine the serum esrtadiol levels. ResultsWith an increase of age, the level of serum E2 in women with normal pregnancy significantly increased (r=0.94, P<0.05), while, the serum E2 level in women with threatened abortion was significantly lower than that in normal pregnancy at the same gestational age. ConclusionThe serum level E2 is significantly decreased in women with threatened abortion, suggesting that serum E2 should be an important factor supporting early pregnancy.

Key words: Estradiol, Pregnancy, Abortion, threatened

CLC Number: 

  • R714.4
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