Abstract: Objective To explore the risk factors for death within 2 years in patients newly admitted to maintenance haemodialysis(MHD). Methods The 2-year clinical data of patients who started haemodialysis from March 2019 to November 2020 in The Second Hospital, Cheeloo College of Medicine, Shandong University were retrospectively collected. They were divided into death group and survival group according to whether they had died at 2 years. The clinical data were compared and the risk factors for death were analyzed. The patients were grouped by pre-dialysis systolic blood pressure(SBP)to compare the impact of blood pressure. Finally, the independent risk factors for patient death were analyzed using univarite and mnltivariate Cox regression models. Results During the observation period, a total of 83 patients were newly admitted to MHD, 4 left within 2 years, and 3 received renal transplant. Of the 76 cases included, 17(22.4%)died. Compared with the survival group, patients in the death group had lower blood potassium, albumin, blood creatinine, and SBP at baseline, a higher proportion of comorbid coronary artery disease and diabetes mellitus, and a higher estimated glomerular filtration rate; patients with an SBP ≤140 mmHg(1 mmHg=0.133 kPa)had a higher case-fatality rate. Cox regression analysis revealed that the lower pre-dialysis SBP(HR=0.957, 95%CI: 0.928-0.987), albumin(HR=0.918, 95%CI: 0.857-0.984), and comorbid diabetes mellitus(HR=3.690, 95%CI: 1.157-11.768)were found to be independent risk factors for death in patients(P<0.05). Conclusion Newly admitted MHD patients have a high case-fatality rate; SBP≤140 mmHg suggests higher risk of death; lower pre-dialysis SBP, albumin, and comorbid diabetes mellitus are risk factors for their death within 2 years.

Key words: Maintenance haemodialysis, Pre-dialysis blood pressure, Risk of death, Risk factors