Journal of Shandong University (Health Sciences) ›› 2018, Vol. 56 ›› Issue (10): 46-50.doi: 10.6040/j.issn.1671-7554.0.2018.1035

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Applications of digital PCR in cancer detection and treatment

GUAN Ming, ZHANG Xinju   

  1. Department of Central Laboratory, Huashan Hospital Affiliated to Fudan University, Shanghai 200040, China
  • Received:2018-09-04 Online:2018-10-10 Published:2022-09-27

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Abstract: Digital PCR is a novel technique that facilitates the absolute quantitation of nucleic acid targets with high sensitivity. Digital PCR combined with liquid biopsies can be used in the detection of infinitesimal nucleic acid samples and rare mutations. It is particularly suitable for cancer patients who need repeated sampling. Digital PCR can provide adequate gene information in cancer diagnosis and relapse monitoring.

Key words: Digital PCR, Liquid biopsy, Genetic testing, Absolute quantitation, Cancer

CLC Number: 

  • R73-34
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