JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES)

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Yinxingdamo combined with Lovastatin for acute cerebral infarction

ZHAO Bin1, MA Yong-chun2   

  1. 1. West Campus Hospital of Shandong University, Jinan 250012, China;
    2. First Department of Internal Medicine, Yuncheng People′s Hospital, Yuncheng 274700, Shandong,　China
  • Received:2008-05-09 Revised:1900-01-01 Online:2008-09-16 Published:2008-09-16
  • Contact: ZHAO Bin

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Abstract: To explore the therapeutic effects of Yinxingdamo combined with Lovastatin in treatment of acute cerebral infarction. Methods 127 patients with acute cerebral infarction were randomly divided into three groups. The Chuanxiongqin group was subjected to Chuanxiongqin injection 200mg+Ns250mL, ivdrip, Qd, for 14 days; the Yinxingdamo group was subjected to Yinxingdamo injection 20mL+NS250mL, ivdrip, Qd, for 14 days; the combination group was subjected to the Yinxingdamo injection 20mL+NS250mL, ivdrip, Qd, and Lovastatin 40?mg, PO, QN. 14 days later, Yinxingdamo was disused and Lovastatin was continued. The therapeutic effects were evaluated after 30 days. ResultsThe response rate of the combination group was higher than that of the Yinxingdamo group（P＜0.05） and the Chuanxiongqin group（P＜0.01）. The degree of NFD and the levels of serum lipids and whole blood viscosity, and the plasma viscosity were significantly decreased（P＜0.01）. However, the HDLC level was significantly increased（P＜0.01）. ConclusionLovastatin combined with Yinxingdamo has obvious therapeutic effects on acute cerebral infarction, and it can improve the neurological function and decrease the levels of serum lipids and blood viscosity.

Key words: Lovastatin, Yinxingdamo, Chuanxiongqin, Cerebral infarction

CLC Number: 

  • R743.33
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