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Effects of bite force absence on alveolar bone absorption in osteoporosis rats

WANG Xu-xia, ZHANG Jun, LIU Mei, XUE Li-wei, BU Tao   

  1. Department of Oral & Maxillofacial Surgery, School of Stomatology, Shandong University, Jinan 250012, China

  • Received:1900-01-01 Revised:1900-01-01 Online:2008-08-16 Published:2008-08-16
  • Contact: ZHANG Jun

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Abstract:

Objective〓〖WTBZ〗To explore the effects of bite force absence on alveolar bone absorption in osteoporosis rats by operation. 〖WTHZ〗Methods〓〖WTBZ〗Forty three-month old Wistar rats were randomly divided into the sham operation group(SO), the loss of stress group(LS)， the ovariectomized group (OVX)，and the ovariectomized with loss of stress group (OVX+LS). Female castration and one side molar absence were prepared by operations. Levels of ALP，Ca and P of blood serum were determined at the 8th and 12th week after the operations, also the bone mineral density (BMD) was determined by the Dual-energy X-ray absorption method. 〖WTHZ〗Results〓〖WTBZ〗ALP of blood serum was increased and the mandible mineral density was degraded in the OVX group, also the mandible mineral density was decreased more significantly in the OVX+LS group after twelve weeks. 〖WTHZ〗Conclusion〓〖WTBZ〗Bite force absence aggravates alveolar bone absorption in osteoporosis rats.

Key words: Bite force, Osteoporosis, Alveolar bone loss, Rats, inbred strains

CLC Number: 

  • R782.1
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