Abstract:

Objective〓〖WTBZ〗To investigate the relationship between apolipoproteins A5 and lipids metabolism in elderly people. 〖WTHZ〗Methods〓〖WTBZ〗The level of serum total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), apolipoproteinA1 (APOA1), apolipoproteinB100(APOB100) and glucose were determined in 187 elderly people, and APOA5 in 1mL serum was determined under -80℃ by the ELISA method. 〖WTHZ〗Results〓〖WTBZ〗The APOA5 level was negatively correlated with plasma TG level (P＜0.01) and had a positive tendency with the plasma HDL cholesterol, APOA1 and glucose levels and a negative tendency with TC, LDL cholesterol and APOB100 levels, but the difference was not significant (P＞0.05). The APOA5 level was higher in mean than in women, but the difference was also not significant(P＞0.05). 〖WTHZ〗Conclusion〓〖WTBZ〗The APOA5 level is negatively related to the plasma TG level. APOA5 may be an important regulatory mechanism in TG metabolism.

Key words: Apolipoprotein A5, Lipoproteins, HDL cholesterol, Liporoteins, LDL cholesterol, Blood glucose, Sex