JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES)

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Morning blood pressure surge and target organ damage

ZHENG Xia1，WANG Xin2，ZHU Yan-li2，LI Wen-hua2，GAO Hai-qing3   

  1. 1.Electrocardiogram Room, Shandong Provincial Hospital；2.Department of Cardiac Diseases, Shandong Provincial Hospital；3.Department of Cardiac Diseases, Qilu Hospital of Shandong University
  • Received:2007-02-03 Revised:1900-01-01 Online:2007-08-24 Published:2007-08-24
  • Contact: ZHENG Xia

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Abstract: Objective： To investigate the role of morning hypertension on cardiac structure and electrophysiology and on kidney and blood vessel endothelium damage. Methods： A total of 201 cases were divided into two groups: the morning blood pressure surge group and the morning blood pressure normal group based on the 24-hour ambulate blood pressure monitoring profiles. Blood fat, microalbuminuria, body mass index（BMI）, left ventricular mass index（LVMI）and QT dispersion（QTcd）were determined. Results： LVMI, QTcd and microalbuminuria in the surge group were higher than those in the normal group （P＜0.01）.There were no significant differences between the two groups in gender, age, BMI, and hypertension course. Conclusions： Morning blood pressure surge can cause ventricular hypertrophy and reconstitution and cardiac conduction arrhythmia, changes blood vessel function, damages the heart, kidney and blood vessel endothelium, and so accelerates atherogenesis.

Key words: Hypertension, Morning blood pressure surge, Target organ damage, Ambulatory blood pressure monitoring

CLC Number: 

  • R544.1
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