JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES)

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Comparison of flow-sensitive alternating inversion recovery and dynamic susceptibility constrast MR perfusion technique in evaluating intracranial tumor vascularization

ZHANG Kai1，LI Chuan-fu1， LIU Ying2，FENG De-chao1，MENG Xiang-shui1，ZHENG Jin-yong1，CONG Pei-xin1   

  1. 1. Department of Radiology, Qilu Hospital of Shandong University；2. Department of Radiology, Anhui Provincial Hospital, Hefei 230001
  • Received:2006-07-19 Revised:1900-01-01 Online:2007-06-24 Published:2007-06-24
  • Contact: ZHANG Kai

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Abstract: Objective: To compare the effects of flowsensitive alternating inversion recovery (FAIR) and dynamic susceptibility contrast MR (DSCMR) perfusion technique in evaluating intracranial tumor vascularization. Methods: Thirtythree patients suffering from intracranial tumors were determined by using the FAIR and DSCMR perfusion techniques. The values of FAIR and CBV were recorded and analyzed by the linear correlation analysis method. The values of FAIR and CBV between benign and malignant gliomas were statistically analyzed. Results： There was a positive linear correlation between FAIR and CBV(r=0.450，P=0.009). The difference of the CBV value between benign and malignant gliomas was statistical (Z=-2.213，P=0.027). So was that of the FAIR value (Z=-2.021，P=0.043). Conclusion： FAIR does not need a contrast agent and could offer some comparable perfusion information to DSCMR technique to clinicians, so it has the potential to be clinically applied.

Key words: Magnetic resonance imaging, Hemoperfusion, Spin labels, Central nervous system neoplasms

CLC Number: 

  • R445.2
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