JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES)

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Relationship between the autonomic dysreflexia and calcitonin gene-related peptide in rats following an acute spinal cord injury

HU Kui, LIU Pei-lai, ZHANG Yuan-kai, DING Ming, ZHOU Lei, LI Ming   

  1. Department of Orthopedics, Qilu Hospital of Shandong University, Jinan 250012, Shandong, China
  • Received:1900-01-01 Revised:1900-01-01 Online:2007-04-24 Published:2007-04-24
  • Contact: HU Kui

Abstract: Objective: To study the relationship between the autonomic dysreflexia(AD) and positive neurons of calcitonin gene-related peptide(CGRP) in rats following an acute spinal cord injury. Method: Changes of the AD and the dendrite of the CGRP positive neurons were produced at the day of 0, 3, 6, 9, 12, and 15 in Wistar rats following an acute spinal cord injury (SCI). Result: CGRP increased in a time-dependent manner by the quadratic function in 15 days. There was correlation between the AD and the restitution of the CGRP positive neurons. Conclusion: CGRP increases in a timedependent manner by the quadratic function. There are relationships between AD and CGRP positive neurons.

Key words: Spinal cord injury, Autonomic dysreflexia, Calcitonin gene-related peptide, Rats, Wistar

CLC Number: 

  • R681.54
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