Abstract: Objective： To explore the factors affecting short-term prognosis of acute myocardial infarction(AMI) patients with prodromal angina pectoris( AP).Methods： From October 2001 to December 2004, 234 AMI patients with previous angina pectoris(AP) (group A)and 255 AMI patients without AP (group B)were studied. In group A, 147 patients received intravenous thrombolysis( A₁ group) and 87 received PCI( A₂ group). In group B, 70 patients received intravenous thrombolysis (B₁group) and 185 received PCI (B2 group). The clinical data and the presence of cardial death, left ventricle function failure, arrhythmia, recurrent myocardial infarction were analyzed. Result： ① The clinical and combined endpoint events were not different between A and B group; ② The peak creatine kinase (CK) and CK-MB［(2386±1271)IU/Lvs(3060±1241) IU/L, P＜0.001；(166±94)IU/Lvs(198±127) IU/L, P＜0.05］ were lower, left ventricle function failure, recurrent myocardial infarction, cardial death and combined endpoint events were all lower in A group［10.9%　vs　25.7%, P＜0.01;6.8%　vs　18.6%;44.9%　vs　60.0%,　all P＜0.05］. Diabetes, hyperglycemia correlated with cardial dearth, arrhythmia, recurrent myocardial infarction （P＜0.01、　P＜0.05、 P＜0.05 respectively ）,　the elder, coronary heart disease correlated with arrhythmia(P＜0.05、　P＜0.01 respectively) In A group. Multivariate Logistic regression indicated that left ventricle function failure Independent correlates with arrhythmia, recurrent myocardial infarction(OR: 14.9,CI:4.39-50.39, P＜0.001; OR:26.4,CI: 15.73-121.64, P＜0.01); cardial death is independently related with left ventricle function failure (OR: 84.0,CI :9.20-767.31, P＜0.01); arrhythmia correlates with left ventricle function failure, hyperglycemia independently (OR: 14.71,CI:4.57-47.62, P＜0.001; P＜0.001)；　③ The combined endpoint events were no difference between A₂group B₂ group. Conclusions： AP can reduce the combined endpoint events of AMI that received intravenous thrombolysis. But diabetes and hyperglycemia can counteract the profitable effect of AP in patients with AMI received intravenous thrombolysis. The elder、 coronary heart disease、 left ventricle function failure can decrease the profitable effect of AP in patients with AMI received intravenous thrombolysis.

Key words: Myocardial infarction, Angina, Preinfartion, Isohemic Preconditioning, Prognosis