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Intravenous ketamine combined with epidural anesthesia for laparoscopic cholecystectomy

LI Chuan-gang1，ZHANG Dong-hai1，ZHAO Qiao-jing1，PAN Xiao-jun2   

  1. 1. Department of Anesthesia, Second Hospital of Shandong University, Jinan 250033；2. Department of Anesthesia, Qilu Hospital of Shandong University, Jinan 250012
  • Received:2005-09-07 Revised:1900-01-01 Online:2007-02-24 Published:2007-02-24
  • Contact: PAN Xiao-jun

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Abstract: Objective: To observe the response and safety of intravenous ketamine combined with epidural anesthesia on laparoscopic cholecystectomy. Method: In this study, 40 patients undergoing laparoscopic cholecystectomies were anesthetized with epidural anesthesia（control group） and the other 40 patients were anesthetized with intravenous ketamine combined with epidural anesthesia(ketamine group). The response to anesthesia and the changes of mean blood pressure(MAP), heart rate(HR), SPO2 as well as PaO2 and PaCO2 were observed. Results: The anesthesia effect of the ketamine group was better than that of the control group. The MAP and HR in the ketamine group were more stable than in the control group and there were no statistical differences in PaO2 and PaCO2 between the two groups. Conclusion: Administration of ketamine is beneficial to epidural anesthesia in laparoscopic cholecystectomy. This method can be used safely and effectively in clinical cases.

Key words: Laparoscope, Ketamine, Anesthesia, epidural

CLC Number: 

  • R614.4
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