山东大学学报 (医学版) ›› 2018, Vol. 56 ›› Issue (11): 48-52.doi: 10.6040/j.issn.1671-7554.0.2018.176
王志强1,徐艳龙1,肖长春2,冯晓亮1,郑莉1,李飞1,黄发源3
WANG Zhiqiang1, XU Yanlong1, XIAO Changchun2, FENG Xiaoliang1, ZHENG Li1, LI Fei1, HUANG Fayuan3
摘要: 目的 评估合肥市2014~2016年PM2.5日均浓度对循环系统疾病死亡效应的影响。 方法 从合肥市气象局、环保局获得2014~2016年气象、环保资料,从中国疾病预防控制中心的死因监测系统获取人群死亡资料。采用基于Poisson回归的广义线性模型控制时间趋势、温度、相对湿度、星期几效应、法定节假日等因素,分析污染物PM2.5浓度对因循环系统疾病死亡效应,包含当日(lag0)、滞后(lag1~lag5)和累积滞后(lag01~lag05)效应;分析了老年人组(≥60岁)和非老年人组(<60岁)间PM2.5浓度与循环系统疾病死亡人数的影响,同时分析引入SO2、NO2、O3污染物后,对PM2.5浓度与循环系统疾病死亡人数效应的影响。 结果 PM2.5浓度对因循环系统疾病总死亡人数有显著影响,其中对当日(lag0)和累积滞后5 d(lag05)影响最大,lag0超额死亡危险风险(ER)为0.53%(95%CI: 0.09%~0.98%),lag05的ER为1.01%(95%CI: 0.33%~1.70%)。在老年人组(≥60岁)中,PM2.5浓度对因循环系统疾病总死亡人数的效应更加显著,也是对lag0和lag05影响最大,lag0的ER为0.57%(95%CI: 0.11%~1.03%);lag05的ER为1.04%(95%CI: 0.33%~1.76%)。而在非老年人(年龄<60岁)人群中,PM2.5浓度对因循环系统疾病总死亡人数影响无统计学意义。在多污染物模型分析中,加入污染物SO2、NO2后,发现均可减弱PM2.5对循环系统疾病死亡人群的影响,效应无统计学意义。 结论 2014~2016年PM2.5污染物能增加合肥地区循环系统疾病死亡人数,且在老年人中效应更显著。
中图分类号:
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