妊娠期异常高脂血症2例报告并文献复习

doi:10.6040/j.issn.1671-7554.0.2021.0104

摘要/Abstract

摘要： 目的分析2例妊娠期异常高脂血症病例并复习相关文献,为临床工作处理类似情况提供参考。方法回顾了山东大学齐鲁医院产科收治的2例妊娠期异常高脂血症病例的临床资料。结果此2例病例中,1例合并糖尿病,并发高胆汁酸血症,因胎盘早剥于孕33⁺¹周行剖宫产术;另1例合并妊娠期糖尿病(GDM),因巨大儿于40⁺¹周行剖宫产术。2例新生儿出生后Apgar评分均正常,且无高脂血症。结论对于异常高脂血症的孕妇,需要密切关注其血脂、血糖、肝肾功能等指标及有无胰腺炎、胎盘早剥等发生。高脂血症本身并非剖宫产的指征,但若出现了胎盘早剥等情况,则需行剖宫产术终止妊娠。

关键词: 高脂血症, 妊娠期血脂异常, 高胆汁酸, 肝内胆汁淤积症, 妊娠

Abstract: Objective To analyze 2 cases of abnormal hyperlipidemia during pregnancy and review the related literature, so as to provide reference for clinical work when dealing with similar situations. Methods Clinical data of 2 cases of abnormal hyperlipidemia during pregnancy admitted to the Department of Obstetrics, Qilu Hospital of Shandong University was reviewed. Results One case was complicated with diabetes and hyperbileacidemia, and had a cesarean section at 33⁺¹ weeks of pregnancy due to placental abruption. Another case was combined with gestational diabetes mellitus(GDM), and a cesarean section was performed at 40⁺¹ weeks for a giant baby. The Apgar scores of the two newborns were normal after birth, and no hyperlipidemia occured. Conclusion Pregnant women with abnormal hyperlipidemia should be paid close attention to their blood lipids, blood sugar, liver and kidney function and other indicators, as well as the occurrence of pancreatitis and placental abruption. Hyperlipidemia itself is not an indication for cesarean section, but if placental abruption occurs, cesarean section is required to terminate the pregnancy.

Key words: Hyperlipidemia, Dyslipidemia during pregnancy, High bile acid, Intrahepatic cholestasis, Pregnancy

中图分类号:

R714

龙宇晗,罗霞,姜洁. 妊娠期异常高脂血症2例报告并文献复习[J]. 山东大学学报 (医学版), 2021, 59(3): 103-106.

LONG Yuhan, LUO Xia, JIANG Jie. Abnormal hyperlipidemia during pregnancy: a report of 2 cases and literature review[J]. Journal of Shandong University (Health Sciences), 2021, 59(3): 103-106.

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