青光眼患者视网膜神经纤维层厚度与对应视野缺损的相关性研究

摘要/Abstract

摘要： 目的探讨青光眼患者视乳头不同方位视网膜神经纤维层厚度与对应区域视野缺损之间的相关性。方法对40名有过急性发作史、眼压控制在25 mmHg以下2周以上的原发急性闭角型青光眼患者,采用光学相干断层成像技术(OCT)进行6个方位的视神经纤维层(RNFL)厚度检测和全自动视野计进行72点视野检查。比较患者的颞上、颞下及平均视网膜神经纤维层厚度与对应区域鼻下、鼻上及平均视野缺损之间的关系。结果颞下RNFL厚度与鼻上视野缺损具有高度相关性(r=-0.81,P<0.05),颞上RNFL厚度与鼻下视野缺损具有高度相关性(r=-0.83,P<0.05),平均RNFL厚度与平均视野缺损具有负相关(r=-0.62,P<0.05)。结论 RNFL厚度一定程度上可以反映视野缺损深度。

关键词: 孕妇, 视网膜神经纤维层厚度, 破伤风, 护理, 免疫, 光学相干断层成像技术, 视野缺损

Abstract: Objective To investigate the correlation between the thickness of retinal nerve fiber layer(RNFL) and corresponding visual field defect in glaucoma patients. Methods Forty angle-closure glaucoma patients were enrolled. Optical coherence tomography (OCT) was performed to obtain the thickness of RNFL in 6 positions of optic nerve head and the corresponding visual field sensitivity or visual field defect. Association was analyzed between thickness of temporal-superior RNFL and the visual field defect of nasal-inferior, between the thickness of temporal-inferior RNFL and the visual field defect of nasal-superior, between the thickness of mean RNFL and mean field defect. Results Linear correlation was found between the temporal-superior RNFL thickness and the nasal-inferior visual field defect (r=-0.83), between the temporal-inferior RNFL thickness and the nasal-superior visual field defect(r=-0.80). The negative correlation (r=-0.60) was found between the mean thickness of RNFL and the mean visual defect. Conclusion The thickness of RNFL can partly reflect the depth of the visual field defect.

Key words: OCT, RNFL, visual field defect

中图分类号:

R775.2

曹国凡, 薛劲松, 姚进, 蒋沁. 青光眼患者视网膜神经纤维层厚度与对应视野缺损的相关性研究[J]. 山东大学学报（医学版）, 2014, 52(S1): 68-70.

CAO Guo-fan, XUE Jin-song, YAO Jin, JIANG Qin. Study on correlation between thickness of retinal nerve fiber layer and visual field defect in glaucoma patients[J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2014, 52(S1): 68-70.

参考文献

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