山东大学学报 (医学版) ›› 2024, Vol. 62 ›› Issue (5): 1-6.doi: 10.6040/j.issn.1671-7554.0.2024.0121
• 慢性气道疾病的精准个体化诊疗——专家综述 •
张锦涛,董亮
ZHANG Jintao, DONG Liang
摘要: 气道上皮通过与免疫细胞的紧密互作精细调控并维持气道微环境的形成,在哮喘免疫病理进展过程中处于核心地位。气道上皮源性细胞因子被认为在触发和维持哮喘气道炎症中担任关键角色,成为目前哮喘新型药物研发的热门靶点。本文综述气道上皮及其源性细胞因子在哮喘中的作用及相关靶向药物研究进展,为相关研究提供新视角与新思考。
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