男性骨质疏松:一个长期被忽视的问题

doi:10.6040/j.issn.1671-7554.0.2021.0467

摘要/Abstract

摘要： 骨质疏松症是一种全身性骨病。骨量减少和骨微结构破坏使骨的脆性增加,最终导致骨折风险增加。按照病因不同可将原发性骨质疏松分为绝经后骨质疏松(PMO)和老年性骨质疏松(SO)。而男性骨质疏松主要为SO,所以男性比女性发病晚。目前骨质疏松诊断主要依据双能X线吸收法(DXA)的T值及DXA的流调结果,显示男性骨质疏松患病率低,因此受到重视不够。另外,目前治疗骨质疏松的药物男性适应证少,造成对男性的骨质疏松防治的忽视。所以应该采用多种检测手段,包括影像检查、DXA和定量CT(QCT)对骨质疏松进行诊断,以及加强人们对男性骨质疏松的认知和对干预的重视。

关键词: 骨质疏松, 男性, 双能X线吸收法, 定量化CT, 抗骨质疏松治疗

Abstract: Osteoporosis is a systemic bone disease. The loss of bone mass and the destruction of bone microstructure increase bone fragility and ultimately lead to an increased risk of fracture. According to etiology, primary osteoporosis can be divided into postmenopausal osteoporosis(PMO)and senile osteoporosis(SO). Osteoporosis in men is mainly SO, so the onset of osteoporosis in men is later than that in women. Due to the current dependence on dual X-ray absorptiometry(DXA)in the diagnosis of osteoporosis and the survey results of DXA, the prevalence of osteoporosis in men is considered low. In addition, there are few indications of drugs for the treatment of osteoporosis in men, resulting in the overlook of the prevention and treatment of osteoporosis in men. Therefore, it is necessary to increase the application of various testing methods, including radiology, DXA and QCT in the diagnosis of osteoporosis, as well as strengthen the awareness of osteoporosis in men and its intervention.

Key words: Osteoporosis, Male, Dual X-ray absorptiometry, Quantitative computed tomography, Anti-osteoporosis therapy

中图分类号:

R574

程晓光,卢艳慧. 男性骨质疏松:一个长期被忽视的问题[J]. 山东大学学报 (医学版), 2021, 59(6): 5-9.

CHENG Xiaoguang, LU Yanhui. Osteoporosis in men: a chronically overlooked problem[J]. Journal of Shandong University (Health Sciences), 2021, 59(6): 5-9.

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