关键词: 子宫内膜异位症;  危险因素;  病例对照研究 ; Logistic回归

Abstract:

Objective   To investigate the  hospitalbase incidence of endometriosis among women with different ages and the risk factors associated with endometriosis.  Methods   A case control study was carried out in Jinan including 346 endometriosis patients and 346 healthy people. The data were collected and analyzed with single factor analysis and multivariate unconditional logistic regression analysis among age, individual aspects, menstrual characteristics and reproductive activity. Results   ① The age peak of incidence of endometriosis was between 25 and 50. ② Single factor analysis showed that occupation as cadre and mechanics, college educated, A and O blood types, menarche before or just at age 13, menstrual cycle <27days,menstruallengths >or=8 days, dysmenorrhea, one live birth, abortion numbers >or=2, infertility and intrauterine device use were identified as risk factors. There were significant differences between the two groups(P<0.05). ③ Multifactor analysis confirmed that the risk factors associated with endometriosis included early menarche, short cycles, long menstrual lengths and more abortions numbers. Pregnancy number and labor number were proved to be the protective factors. Conclusion   Endometriosis seemed to be related to early menarche, short cycles, long menstrual lengths, and more abortions numbers.

Key words: Endometriosis；  Risk factor;  Case control study; Logistic regression