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山东大学学报(医学版) ›› 2010, Vol. 48 ›› Issue (6): 1-4.

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2型糖尿病下肢血管病变与血清同型半胱氨酸的关系

何俊1, 张栩2, 管庆波2,  赵家军2,  杜希惠3   

  1. 1.  沂源县人民医院内分泌科,  山东, 沂源 256100;2. 山东大学附属省立医院内分泌科,济南 250021;
    3. 山东大学图书馆,济南 250100
  • 收稿日期:2010-02-26 出版日期:2010-06-16 发布日期:2010-06-16
  • 通讯作者: 张栩(1969- ),男,副主任医师,博士,主要从事糖尿病及其慢性并发症的研究。 E-mail:zhangxu@medmail.com.cn
  • 作者简介:何俊(1965- ),男,副主任医师,主要从事糖尿病及其慢性并发症的研究。 E-mail: yiyuanhj@163.com
  • 基金资助:

    山东省优秀中青年科学家奖励基金(2006BS03012);山东省医药卫生科技发展计划项目(2009HW058);2008人事部留学人员科技活动项目择优经费资助。

Relationship of peripheral artery disease with serum homocysteinein patients with type 2 diabetes mellitus

HE Jun1,  ZHANG Xu2,  GUAN Qingbo2,  ZHAO Jiajun2, DU Xihui3   

  1. 1. Department of Endocrinology, People′s Hospital of Yiyuan County, Yiyuan 256100, Shandong, China;
     2. Department of Endocrinology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan 250021, China;
    3. Library  of  Shandong University,Jinan 250100,China
  • Received:2010-02-26 Online:2010-06-16 Published:2010-06-16

摘要:

目的  探讨2型糖尿病患者下肢血管病变与血清同型半胱氨酸(Hcy)的关系。方法  选择325例2型糖尿病患者,其踝肱指数(ABI)< 0.90 的患者为下肢血管病变组(PAD组,n=115),ABI介于0.90与1.3之间(0.90≤ABI≤1.3)的患者为非PAD组 (n=186)。对ABI<0.90患者: ABI≤0.5为重症下肢缺血组(n=25),0.5

关键词: 2型糖尿病;下肢血管病变;同型半胱氨酸

Abstract:

Objective  To explore the relationship between peripheral artery disease (PAD) and serum homocysteine in patients with type 2 diabetes mellitus. Methods  325 cases of type 2 diabetes were chosen, and ankle-brachial index (ABI) was screened by Doppler ultrasonic examination, and PAD was defined as an anklebrachial index <0.90 in either leg. The PAD patients were categorized by ABI level as follows: severe PAD(ABI ≤0.5), moderate PAD (0.5

Key words: Type 2 diabetes mellitus; Peripheral artery disease; Homocysteine

中图分类号: 

  • R587. 1
[1] 米念荣1,孟超1,王淑芳2. 二甲双胍对初发2型糖尿病患者同型半胱氨酸和颈动脉内膜厚度的影响[J]. 山东大学学报(医学版), 2011, 49(7): 6-.
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