JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES)

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18F-FDG PET-CT for lymph node staging in non-small cell lung cancer

ZHANG Cheng-qi1，WANG Guang-li2，SONG Ji-qing2，YAO Shu-zhan2，LIU Qing-wei2，CHE Jing2   

  1. 1. Department of Radiology, Shandong Qianfoshan Hospital；2. Department of Radiology, Shandong Provincial Hospital, Jinan 250021, Shandong, China
  • Received:2007-04-09 Revised:1900-01-01 Online:2007-10-24 Published:2007-10-24
  • Contact: ZHANG Cheng-qi

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Abstract: Objective： To investigate the clinical value of 18F-FDG PET-CT for non-small cell lung cancer in lymph node staging. Methods：18F-FDG PET-CT (Discovery LS PET-CT in Department of Radiology of Shandong Provincial Hospital) images of 79 patients who had undergone surgeries for histopathologically proved non-small cell lung cancers without distant metastases were analyzed. PET-CT results were compared with the CT data. Findings of both modalities were compared with pathological results and were statistically analyzed. Results： There were 268 lymph node metastases in 79 patients. The sensibility, specificity and accuracy of PET-CT and CT for detecting lymphoid node metastasis were 82.84%, 96.70% and 89.83% and 58.58%, 72.89% and 65.80%, respectively. The former was obviously better than the latter. Overall tumor stage was correctly classified as N stage with CT in 58 patients and with PET-CT in 73 patients. Differences in the accuracy of lymphoid node staging between PET-CT and CT were significant (χ2=10.05, P＜0.01). Conclusion： PET-CT is a very effective imaging modality for lymph node staging of nonsmall cell lung cancer.

Key words: Lung neoplasms, Tomography, emission-computed, Tomography, X-ray computed, Diagnosis, Neoplasm staging

CLC Number: 

  • R817.4
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