Journal of Shandong University (Health Sciences) ›› 2026, Vol. 64 ›› Issue (6): 77-85.doi: 10.6040/j.issn.1671-7554.0.2025.0573

• Public Health and Preventive Medicine • Previous Articles    

Latent profile analysis of financial toxicity and its influencing factors in patients with enterostomy

WANG Jing1, YAN Yishan2, XIAO Lulu1, WANG Ziling1, LIU Yahong1, LIU Rui1, CHAO Qun1   

  1. 1. Department of Neurology, General Hospital of Eastern Theater Command of the Chinese Peoples Liberation Army, Nanjing 210002, Jiangsu, China;
    2. Department of Nursing, Tianjin Medical University Cancer Institute &
    Hospital, Tianjin 300060, China
  • Published:2026-06-29

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Abstract: Objective To explore the potential categories of financial toxicity in patients with enterostomy using latent profile analysis(LPA)and to analyze their influencing factors, aiming to provide a basis for developing targeted intervention strategies. Methods From April to September 2023, a total of 512 patients from the enterostomy clinic of a Grade A tertiary hospital in Tianjin were selected by convenience sampling. Data were collected using a general information questionnaire, the Family APGAR index, the Comprehensive score for Financial toxicity-functional assessment of chronic illness therapy, and the Functional assessment of chronic illness therapy-spiritual well-being scale. Latent profile analysis was performed using Mplus 8.3, and multivariate logistic regression analysis was conducted using SPSS 21.0 to identify influencing factors. Results The financial toxicity of enterostomy patients could be classified into three latent profiles: the non-financial toxicity group(17.19%), the mild financial toxicity group(47.27%), and the moderate financial toxicity group(35.54%). Multivariate logistic regression analysis revealed that lower family care, lower spiritual well-being, lower educational level, medical payment methods of urban resident medical insurance or new rural cooperative medical care, and a per capita monthly household income in the range of 1,001-3,000 yuan were independent factors influencing patients classification into higher financial toxicity profiles(P<0.05). Conclusion There is significant heterogeneity in financial toxicity among enterostomy patients, influenced by both objective economic conditions and subjective psychosocial resources. Healthcare professionals should implement stratified management based on the characteristics of different profiles and construct a comprehensive intervention model integrating medical, psychological, and family support to precisely alleviate patients financial toxicity.

Key words: Colorectal cancer, Enterostomy, Financial toxicity, Family care, Spiritual health, Latent profile analysis

CLC Number: 

  • R735.3
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