JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES)

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GE Xu-ming,PANG Ming,LUAN Li-ming,WANG Han-bin,ZHAO Guang-yu,XU Shang-chen   

  • Received:2005-09-14 Revised:1900-01-01 Online:2006-10-24 Published:2006-10-24
  • Contact: GE Xu-ming

Abstract: Objective: To examine the differential expression of genes related to signal transduction in intracranial aneurysm. Methods: Three samples of intracranial aneurysms and of arteria temporalis superficialis were collected respectively. The total RNA, isolated from the tissues, were linear amplificated and hybridized with the Whole Genome BeadChip. The genes related to signal transduction were analyzed. Results: Twentytwo genes related to signal transduction were overexpressed in intracranial aneurysms. Conclusion: Differential expression of signal transduction genes could play a role in the occurrence of intracranial aneurysm.

Key words: Intracranial aneurysm, Genes, Signal transduction

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