Abstract: Objective To investigate the factors influencing the degrees of fatigue in patients with nonacute myocardial infarction after complete revascularization interventions. Methods Clinical data and psychological self-assessment scales were collected from 152 patients at the third month after complete revascularization interventions. Fatigue was classified into 3 levels according to the Multidimensional Fatigue Inventory(MFI-20): mild(2060). The observation indicators were assessed with univariate analysis, and those with statistical and clinical significance were included to Logistic regression model toidentify the influencing factors. Results With the mild fatigue group as the baseline group for comparison, after adjustment of gender, age and examination findings, the risk factors for increasing fatigue included Gensini score(OR=0.984, 95%CI: 0.969-1.000, P=0.048), glycosylated hemoglobin(OR=0.795, 95%CI: 0.651-0.971, P=0.025), anxiety status(OR=0.379, 95%CI: 0.122-0.850, P=0.043), and depressive status(OR=0.461, 95%CI: 0.205-0.965, P=0.041); protective factors for decreasing fatigue were thyrotropin(OR=1.251, 95%CI: 1.025-1.528, P=0.028), hemoglobin(OR=1.027, 95%CI: 1.002-1.052, P=0.034), sleep quality(OR=13.531, 95%CI: 5.317-34.432, P<0.001), and grade of physical exercise(OR=7.389, 95%CI: 2.895-18.878, P<0.001). Conclusion Improving sleep quality and increasing exercise grade, together with relieving anxiety and depression, controlling glycated hemoglobin, and improving blood oxygenation and thyroid function may improve fatigue symptoms.

Key words: Coronary artery disease, Fatigue, Anxiety, Depression, Sleep quality, Gensini score