Abstract: December 2004. Variables including baseline characteristics, inhospital management and outcomes were recorded and compared between different gender groups. Results: Females were generally older than males (67.7±8.5 vs 60.4±11.6 years, P＜0.001) and had a higher prevalence of hypertension（51.40% vs 39.25%, P＜0.001）and diabetes mellitus（28.31% vs 14.69%, P＜0.001).The Killip class greater than or equal to Ⅲ（11.92% vs 5.22%，P＜0.001） and the total cholesterol (TC)＞4.68?mmol/L（73.37% vs 57.22%，P＜0.001）were more common in females. There was no significant difference on the history of previous angina pectoris, myocardial infarction and family coronary heart disease between males and females (64.53% vs 66.85%，P＝0.344；8.91% vs 9.87%，P＝0.519；22.98% vs 20.68%，P＝0.348, respectively）, however, the history of cigarette smoking（69.74% vs 14.71%, P＜0.001) and alcohol drinking（78.49% vs 24.77%，P＜0.001) was more common in males. Reperfusion therapy within the first 24 hours after symptom onset and β－blockers were underused during hospitalization phase in females compared with males (22.16% vs 28.01%, P＝0.010; 64.43% vs 70.14%, P＝0.017, respectively). An increased mortality was demonstrated in females during the hospitalization phase of AMI（11.92% vs 6.90%, P＜0.001). Conclusions: The inhospital mortality of females is higher than that of males following AMI. Females are older and have more risk factors than males, and reperfusion therapy and βblockers are underused, all of which are important causes of the difference on inhospital mortality between male and female patients with AMI.

Key words: Acute myocardial infarction, Sex factors, Mortality