JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES)

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MENG Xiao, LI Li, TAN Hong-wei, QIE Liang-yi, ZHONG Ming, FENG Min, ZHANG Yun   

  1. Department ofCardiology, Qilu Hospital of Shandong University, Jinan 250012， Shandong, China
  • Received:2006-03-12 Revised:1900-01-01 Online:2006-12-24 Published:2006-12-24
  • Contact: MENG Xiao

Abstract: To investigate the longterm effect of Xuezhikang(XZK) on carotid atherosclerosis in patients with myocardial infarction. Methods：Sixtyfive patients with myocardial infarction were given capsule of 0.6?g XZK, twice a day, or placebo in addition to conventional therapy. The mean followup was 5.58±1.05 years. Their carotids and lipid levels were examined with highfrequency ultrasound checked before and after treatment. Results: XZK efficiently decreased the total cholesterol (TC), the low density lipoprotein cholesterol (LDLC), the lowered intimamedia thickness (IMT) and the index of atherosclerosis plaque (P<0.05). Compared with control group, resistence index and stiffness index were significantly lower, and the peak velocity in systolic stage, the end velocity in diastolic stage, the maximal shear rate and distensibility coefficient were significantly higher in XZK group (P<0.05). Conclusions: Longterm treatment of XZK can slow down or prevent the development of carotid atherosclerosis, fade away and reverse the carotid atherosclerosis plaque. What′s more, it can improve the arterial elasticity.

Key words: Carotid atherosclerosis, Xuezhikang, Ultrasomnograph, Myocardial infarctio

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