Journal of Shandong University (Health Sciences) ›› 2022, Vol. 60 ›› Issue (5): 37-42.doi: 10.6040/j.issn.1671-7554.0.2021.0969

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Clinical and imaging characteristics of 4 cases of secondary hypertrophic olivary degeneration

GONG Yu1, GAO Zhen1, WANG Huqing1, YANG Jingwen2, ZHANG Guilian1, ZHAN Shuqin1, ZHANG Ru1, WU Haiqin1   

  1. 1. Department of Neurology, Second Affiliated Hospital of Xian Jiaotong University, Xian 710004, Shaanxi, China;
    2. Department of Neurology, Gansu Provincial Hospital, Lanzhou 730000, Gansu, China
  • Published:2022-06-01

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Abstract: Objective To explore the clinical and imaging characteristics of secondary hypertrophic olivary degeneration(HOD)so as to improve the clinical recognition and diagnosis. Methods The clinical and imaging data of 4 patients treated during Apr. 2019 and Jan. 2020 were retrospectively analyzed, and the mechanism was discussed. Results All cases were secondary HOD. Symptoms of extra-vertebral system appeared, while symptoms of pyramidal system in different lesions of the brainstem and cerebellum were stable. Limited high signal was observed in the enlarged inferior olivary nucleus on T2WI imaging. Conclusion Variant lesions in brain stem or cerebellum may lead to the occurrence of secondary HOD. When extra-vertebral system symptoms appear in addition to stable vertebral system symptoms, HOD should be considered. A clear diagnosis requires appropriate imaging examinations.

Key words: Secondary hypertrophic olivary degeneration, Clinical manifestation, Imaging characteristics

CLC Number: 

  • R742
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