Journal of Shandong University (Health Sciences) ›› 2021, Vol. 59 ›› Issue (6): 10-14.doi: 10.6040/j.issn.1671-7554.0.2021.0324

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Advances on the etiology and pathogenesis of osteoporosis

LUO Xianghang, ZHOU Ruoyu   

  1. Department of Endocrinology, Endocrinology Research Center, Xiangya Hospital of Central South University, Changsha 410008, Hunan, China
  • Published:2021-06-10

Abstract: Osteoporosis is the most common metabolic bone disease. The incidence of osteoporosis as well as osteoporotic fracture increases gradually with age, seriously endangering patients health. The core pathogenesis of osteoporosis is that various factors act on some stages of bone remodeling, resulting in stronger bone resorption than bone formation. These factors include genetic factors, age, endocrine and lifestyle. It is of great significance to study the pathogenesis and etiology of osteoporosis for its prevention and treatment.

Key words: Osteoporosis, Etiology, Pathogenesis, Aging

CLC Number: 

  • R580
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