Abstract: Objective To explore the application value of enhanced recovery after surgery(ERAS)in the perioperative period of uvulopalatopharyngoplasty(UPPP). Methods A total of 84 patients with severe obstructive sleep apnea hypopnea syndrome(OSAHS)were randomly divided into the ERAS group(n=44)and control group(n=40). Both groups underwent UPPP. The ERAS group received a series of optimization measures, and the control group received traditional perioperative management. All patients filled in the hospital anxiety and depression scale(HADS), MOS-SS sleep scale and visual analog scale(VAS). The emotional changes of patients in the ERAS group before and after psychological intervention were recorded. The postoperative sleep quality, degree of discomfort symptoms, waiting time before hospitalization, hospitalization time after surgery and incidence of complications were compared between the two groups. Results The HADS scores reduced from 5(3, 9.75)to 3(2, 5.75)in the ERAS group. The postoperative MOS-SS score was(46.09±4.86)in the ERAS group and(33.43±4.44)in the control group, the perioperative weight loss was(2.30±0.65)kg and(5.12±0.78)kg, respectively, and the differences were statistically significant(P<0.05). The ERAS group had shorter preoperative waiting time and postoperative hospitalization time, and lower VAS scores of postoperative pharyngeal pain, pharyngeal foreign body sensation, dysphagia and dry throat than the control group(P<0.05). There were no statistically significant differences in the incidences of postoperative bleeding, nausea, vomiting, and nasopharyngeal reflux between the two groups(P>0.05). Conclusion The personalized ERAS program can create good physical conditions for UPPP in severe OSAHS patients, reduce their physical and psychological stress, improve medical experience, and promote postoperative recovery.

Key words: Obstructive, Sleep apnea, Enhanced recovery after surgery, Uvulopalatopharyngoplasty