Abstract: Objective To explore negative emotions such as anxiety and depression and related factors for elderly patients with comorbidity of hypertension and diabetes. Methods A total of 600 elderly people (aged over 60) were enrolled in the survey. All subjects filled in anxiety self-rating scale, depression self rating scale and underwent physical examination. Results According to medical records, the subjects were divided into the control group, hypertension group, diabetes group and comorbidity of hypertension and diabetes group. The comorbidity group had higher level of waist-to-height ratio than the other groups (P<0.01). Compared with control group, hypertension group and comorbidity group had obvious anxiety and depression (P<0.01). The correlation analysis showed that gender, educational level, income, type and course of diseases were associated with anxiety; gender, age, educational level, marital status, income, type and course of diseases, waist-to-height ratio, and systolic blood pressure were associated with depression. Regression analysis showed that the educational level, systolic blood pressure and diabetes were negative predictors of anxiety (P<0.01), while course of disease was a positive predictor of anxiety (P<0.01); age and course of disease were positive predictors of depression (P<0.05), while educational level and income level were negative predictors of depression (P<0.01). Conclusion Elderly patients with comorbidity of hypertension and diabetes show obvious anxiety, depression and abnormal physiological indexes. Type and course of disease are significantly associated withanxiety and depression. Age, education level, income level, type and course of disease, and systolic blood pressure are predictors of negative emotions.

Key words: Hypertension, Diabetes, Anxiety, Elderly, Comorbidity, Depression