Abstract:

Objective〓〖WTBZ〗To investigate the distribution of corneal high-order aberrations (HOAs, 3rd to 6th orders) myopic eyes of adolescent, and study the changes as a function of the degree of myopia. 〖WTHZ〗Methods〓〖WTBZ〗Using the iTrace Visual Function Analyzer, root mean square(RMS)of total corneal HOAs, 3rd-,4th-,5th-,6th-order aberrations, coma and SA were determined from the central 6.0mm zone of 104 eyes of 104 subjects mean 19.9±1.34 years old, ranging from 16 to 24 years; mean manifest spherical equivalent was (-3.98±2.50)D. Correlation between corneal HOAs and refractive power was analyzed. 〖WTHZ〗Results〓〖WTBZ〗The mean refractive error was sphere (-3.72±2.36)D and cylinder (-0.77±0.62)D, and the mean RMS of corneal total high order(3rd to 6th) was (0.413±0.134)μm. Values of Zernike coefficients progressively decreased from the 3rd-order to the 6th-order (except Z04). The mean coefficient of the 4th-order SAs(Z04) was (0.272±0.086)μm and was positive in all corneas. No correlation was found between total corneal high order RMS and myopia. However, horizonal primary coma(Z13) statistically correlate with spherical equivalent (SE) （P＜0.01）. Coma was more frequent in high myopia as a dominant aberration, and SA occurred equally around 80%. 〖WTHZ〗Conclusions〓〖WTBZ〗Corneal wavefront aberrations greatly vary among adolescents, while horizontal primary coma(Z13) slightly decreases with an increase of SE. All corneas have positive 4th-order SAs, and the values are negatively correlated with SE in median myopia. Coma is more frequent in high myopia, and SA is the most influential one in cornea aberrations.

Key words: Myopia, Cornea, Wavefront aberration, Adolescence